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Pyruvate dehydrogenase autoantibodies in autoantibody‐negative patients with seizures are associated with reduced pyruvate dehydrogenase activity

open access: yesEpilepsia, EarlyView.
Abstract Objective We investigated the presence and potential functional relevance of antimitochondrial autoantibodies in patients suspicious for autoimmune encephalitis (AIE) associated with psychiatric symptoms and/or seizures, who were negative for known antineuronal autoantibodies.
Annika Breuer   +12 more
wiley   +1 more source

Peripheral lysosome levels dictate mTORC1 inactivation even when catabolically impaired. [PDF]

open access: yesCell Commun Signal
Dang HQ   +7 more
europepmc   +1 more source

Porcine gut loops to explore the impact of amino acids on the host-microbiota crosstalk in the ileum. [PDF]

open access: yesFront Microbiol
Renois F   +9 more
europepmc   +1 more source
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Structure of the leucine zipper

Current Opinion in Genetics and Development, 1992
In the basic-region leucine-zipper domain, flexible DNA-binding arms are juxtaposed by a two-stranded, parallel coiled-coil motif called the leucine zipper. Genetic, physical and structural studies of the leucine zipper identify interactions that help determine the stability and specificity of dimerization and DNA binding.
Tom Alber, T Alber
exaly   +3 more sources

Glucocorticosteroids increase leucine oxidation and impair leucine balance in humans

open access: yesAmerican Journal of Physiology-Endocrinology and Metabolism, 1989
High-dose glucocorticoid treatment results in protein wasting. To determine whether such therapy affects leucine oxidation in the postabsorptive state and the disposal of dietary amino acids, eight normal subjects were studied twice in random order, once after 5 days of prednisone (20 mg three times daily) and on a second occasion without prednisone as
B, Beaufrere   +6 more
openaire   +3 more sources

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