Results 251 to 260 of about 355,417 (306)

Effects of leucine, isoleucine, or threonine infusion on leucine metabolism in humans

open access: yesAmerican Journal of Physiology-Endocrinology and Metabolism, 1987
Leucine and/or its alpha-keto acid, alpha-ketoisocaproate (KIC), have been reported to spare protein in humans. To determine whether specific amino acid infusions affect whole-body protein metabolism as estimated by changes in leucine flux and oxidation, five groups of normal subjects were infused with saline, leucine (0.47 and 0.94 mumol . kg-1 . min-
W F, Schwenk, M W, Haymond
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Leucine

open access: yes, 2022
Inelastic Neutron Scattering spectrum of Leucine, (CH3)2CHCH2CH(NH2)CO2H, measured on the TOSCA instrument.
Ford, R.
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Characterization of leucine-leucine transport in leaf tissues

Journal of Experimental Botany, 1996
Uptake of the dipeptide [3H]Leu-Leu into leaf discs from mature broad bean (Vicia faba L.) was characterized. Uptake was maximal at pH 6.0 and appeared to be mediated by three systems with apparent Km values of 20 µM, 350 µM and 43 mM, respectively.
A, Jamaï   +4 more
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Semisynthesis and biological properties of the [B24-leucine]-, [B25-leucine]- and [B24-leucine, B25-leucine]-analogues of human insulin

Experientia, 1981
Trypsin-catalyzed coupling of porcine desoctapeptide-insulin with synthetic octapeptides produced the [LeuB24]- (I), [LeuB25]- (II) and [LeuB24, LeuB25]- (III)analogues of human insulin. I, II and III displayed respectively 20--30%, 1--2% and 0.5% of the receptor binding activity of the normal hormone. Biological activities of these analogues seemed to
K, Inouye   +5 more
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Leucine kinetics at graded leucine intakes in young men

The American Journal of Clinical Nutrition, 1986
A study was carried out with 12 young men to examine the relationships between the intake of leucine and indices of leucine kinetics, using L-[1-13C]leucine as a tracer. Six subjects received L-amino acid diets during 7-day periods supplying leucine in the range of 79 to 20 mg.kg-1.day-1 (Group I) and another six subjects (Group II) received leucine ...
M M, Meguid   +5 more
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MicroRNA-27a Is Induced by Leucine and Contributes to Leucine-Induced Proliferation Promotion in C2C12 Cells

open access: yesInternational Journal of Molecular Sciences, 2013
Leucine, a branched chain amino acid, is well known to stimulate protein synthesis in skeletal muscle. However, the role of leucine in myoblast proliferation remains unclear. In this study, we found that leucine could promote proliferation of C2C12 cells.
Xiaoling Chen   +2 more
exaly   +2 more sources

Metabolism of leucine in fibroblasts with defects in the leucine catabolic pathway

International Journal of Biochemistry, 1987
1. The activity of the leucine catabolic pathway was measured by quantitation of the radiolabeled glutamic acid produced by intact cultured fibroblasts incubated with radiolabeled leucine. 2. Five normal cell lines produced an average of 179 +/- 47 pmol glutamic acid/mg cell protein/hr. 3.
T, Page, W L, Nyhan
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Addition of leucine precursors to the diet of leucine-starved mice

The American Journal of Clinical Nutrition, 1975
Leucine-starved mice placed on a diet supplemented with the immediate precursor of leucine, alpha-ketoisocaproic acid, regain lost weight. This weight gain is similar to that observed when the leucine-starved mice are provided with leucine in their diet.
M E, Trigg   +4 more
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Self-Assembly of Phenylalanine-Leucine, Leucine-Phenylalanine, and Cyclo(-leucine-phenylalanine) Dipeptides through Simulations and Experiments

The Journal of Physical Chemistry B, 2023
For over two decades, peptide self-assembly has been the focus of attention and a great source of inspiration for biomedical and nanotechnological applications. The resulting peptide nanostructures and their properties are closely related to the information encoded within each peptide building block, their sequence, and their modes of self-organization.
Peter Divanach   +4 more
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Leucine-Induced Hypoglycemia

New England Journal of Medicine, 1962
SPONTANEOUS hypoglycemia in infancy may, on rare occasions, be precipitated by the ingestion of casein, L-leucine or isovaleric acid, an intermediary metabolite of leucine.1 2 3 4 Recently, this phenomenon of "leucine-induced hypoglycemia" was observed to be associated with a rise in plasma insulin level.5 , 6 A case of leucine-induced hypoglycemia in ...
H M, HADDAD   +3 more
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