The odd- and branched-chain fatty acids (OBCFA) accumulated in ruminant products are a class of beneficial fatty acids for human health. Since biotin and leucine are involved in OBCFA synthesis, this study aimed to evaluate their effect on OBCFA ...
Tengfei Zhan+4 more
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A route to anionic hydrophilic films of copolymers of l-leucine, l-aspartic acid and l-aspartic acid esters [PDF]
A series of copolymers of l-leucine and β-benzyl-l-aspartate [Leu/Asp(OBz)] covering the range 30–70 mol % of l-leucine, was synthesized by the N-carboxyanhydride (NCA) method.
Bantjes, A., Feijen, J., Sederel, W.L.
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Plasma Metabolite Signature Classifies Male LRRK2 Parkinson’s Disease Patients
Parkinson’s disease (PD) is a progressive neurodegenerative disease, causing loss of motor and nonmotor function. Diagnosis is based on clinical symptoms that do not develop until late in the disease progression, at which point the majority of the ...
Chen Dong+7 more
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Mutations of penicillin acylase residue B71 extend substrate specificity by decreasing steric constraints for substrate binding [PDF]
Two mutant forms of penicillin acylase from Escherichia coli strains, selected using directed evolution for the ability to use glutaryl-L-leucine for growth [Forney, Wong and Ferber (1989) Appl. Environ. Microbiol.
Brannigan, J A+5 more
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Nutritional Practice and Nitrogen Balance in Elite Japanese Swimmers during a Training Camp
The protein requirement in athletes increases as a result of exercise-induced changes in protein metabolism. In addition, the frequency, quantity, and quality (i.e., leucine content) of the protein intake modulates the protein metabolism.
Ami Mizugaki+4 more
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The combined intake of citrulline (CIT) and leucine (LEU) can stimulate protein synthesis. Therefore, this study aimed to investigate the effect of combined intake of CIT and LEU accompanied by exercise for 20 weeks on body composition, physical activity
Mijin Kim, Hiroko Isoda, Tomohiro Okura
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Hot Electron Capture Dissociation Distinguishes Leucine from Isoleucine in a Novel Hemoglobin Variant, Hb Askew, β54(D5)Val→Ile [PDF]
Population migration has led to the global dispersion of human hemoglobinopathies and has precipitated a need for their identification. An effective mass spectrometry-based procedure involves analysis of the intact α- and β-globin chains to determine ...
B. J. Wild+12 more
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Failure of Excess Leucine to Impact Live Performance and Carcass Traits in Male and Female Cobb MV x 500 Broilers During a 15-to 32-day Grower Period [PDF]
Modern broiler diets may contain excess levels of leucine due to the increased level of this amino acid in cereal grains. Excessive levels of leucine have previously been shown to negatively influence broiler performance due to branched-chain amino acid ...
Butler, L. D.+8 more
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Pharmacological Treatment of Sarcopenia Tratamento medicamentoso da sarcopenia
Sarcopenia has been acquiring a growing importance in the scientific literature and in doctors’ offices. As the population ages, it becomes increasingly essential to know, prevent, and treat this clinical condition.
Caio Gonçalves de Souza
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Diversion of Acetyl CoA to 3-Methylglutaconic Acid Caused by Discrete Inborn Errors of Metabolism
A growing number of inborn errors of metabolism (IEM) have been identified that manifest 3-methylglutaconic (3MGC) aciduria as a phenotypic feature. In primary 3MGC aciduria, IEM-dependent deficiencies in leucine pathway enzymes prevent catabolism of ...
Dylan E. Jones+2 more
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