Results 171 to 180 of about 40,253 (233)

External Auditory Canal Metastasis of Colorectal Adenocarcinoma: A Comprehensive Case Report. [PDF]

Clin Case Rep
Sissa L, Cardelli S, Malvi D, Poggioli G, Rottoli M, Calini G.   +5 more
europepmc   +1 more source

Functional Precision Medicine Using MicroOrganoSpheres for Treatment Response Prediction in Advanced Colorectal Cancer. [PDF]

JCO Precis Oncol
Gobits R, Schleußner N, Oliver GR, Rutenberg Schoenberg M, de Jesus Domingues AM, Ramkumar P, Suen SWF, Koomen MPM, Paolucci F, Martens K, Guiseris Martinez A, Volk J, Artmann C, Mastel M, Ouyang KS, Kloor M, Bankaitis ED, Stoub HE, Puschhof J, Brown K, Pretzer S, Nelson DA, Struminger E, Zessin A, Brown A, Evans C, Yetsko D, Harrington M, Salg G, Schneider M, Schmidt T, Helman E, Plenker D, Barnett C, Jones RT, Köhler B, Driehuis E, Jackstadt R.   +37 more
europepmc   +1 more source

Real-World Evidence of the Efficacy and Safety of Second-Line Therapy After Gemcitabine and Nab-Paclitaxel for Patients with Metastatic Pancreatic Cancer. [PDF]

Cancers (Basel)
Adamczuk-Nurzyńska A, Nurzyński P, Brzozowska M, Jewczak M, Śliwczyński A.   +4 more
europepmc   +1 more source

Vitamins, Vascular Health and Disease. [PDF]

Nutrients
Ayoub G.
europepmc   +1 more source

Atezolizumab and motixafortide, cobimetinib or simlukafusp alfa in pretreated advanced pancreatic cancer: phase I/IIb MORPHEUS-PDAC umbrella study. [PDF]

Oncologist
Manji GA, Chung V, Oh DY, Lacy J, Lopez CD, Ponz-Sarvisé M, Macarulla T, Thomas R, George B, Alistar A, Siveke JT, Xu Y, Lau J, Cha E, Kim KP, O'Reilly EM.   +15 more
europepmc   +1 more source

Efficacy and safety of cinobufacini capsules combined with oxaliplatin-based chemotherapy for advanced colorectal cancer: a human systematic review and meta-analysis. [PDF]

Front Pharmacol
Wang J, Gao Q, Que Y, Zheng D, Chen J.
europepmc   +1 more source

Methotrexate-Induced Encephalopathy Mimicking Acute Ischemic Stroke in an Adolescent With Osteosarcoma: A Case Report. [PDF]

Am J Case Rep
Duong TV, Huong DT, Quy K, Phuong NTM, Hung HQ.   +4 more
europepmc   +1 more source

Correction: Impact of perioperative fluorouracil, leucovorin, oxaliplatin, and docetaxel delivery on postoperative survival in locally advanced oesophagogastric adenocarcinoma. [PDF]

Gastric Cancer
Sugiyama K, Kumar S, Chaudry A, Patel N, Patel P, Cunningham D, Starling N, Rao S, Fribbens C, Chau I.   +9 more
europepmc   +1 more source

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Leucovorin-induced hypersensitivity reaction

Journal of Oncology Pharmacy Practice, 2011
Leucovorin is a reduced form of folic acid, which has multiple uses.1 In this case report, it is used in combination with fluorouracil in the treatment of colon cancer. We describe a 53-year-old male, who was started on FOLFOX 6 + bevacizumab who experienced a hypersensitivity reaction to leucovorin.
Avni, Damaske, Nichole, Ma, Reba, Williams   +2 more
openaire   +2 more sources

Leucovorin as a Prodrug

1993
To exert its antitumor effects, leucovorin must ultimately become activated by conversion to CH2FH4.* Elevation of this reduced folate cofactor stabilizes the inhibitory ternary complex formed between the FU active metabolite, FdUMP and thymidylate synthase, resulting in suppression of DNA synthesis or repair.1–4 It has been demonstrated both in animal
D G, Priest, J C, Schmitz, T, Walle
openaire   +2 more sources