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T lymphocytes subpopulations in B cell chronic lymphocytic leukemia.
N, Cantore +8 more
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Cytokines in B-Cell Chronic Lymphocytic Leukemia
Leukemia & Lymphoma, 1991The pleomorphic action of different cytokines in regulating the growth and proliferation of normal B- and T-lymphocyte populations is becoming progressively more apparent. Thus, the possibility that some cytokines, either alone or in variable combination, may play a role in different lymphoproliferative disorders has been increasingly suggested and ...
FOA, Roberto +7 more
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Cutaneous manifestations of B-cell chronic lymphocytic leukemia
International Journal of Hematology, 2020Chronic lymphocytic leukemia (CLL) is a malignant lymphoproliferative disease characterized by the accumulation of immature monoclonal B lymphocytes in blood cells, bone marrow, spleen and lymph nodes. This is the most common type of leukemia among the Caucasoid race.
Elena A. Morozova +2 more
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Chronic Myelomonocytic Leukemia Coexisting with B-cell Chronic Lymphocytic Leukemia
Leukemia & Lymphoma, 2003Coexistence of B-cell chronic lymphocytic leukemia (B-CLL) and chronic myelomonocytic leukemia (CMML) is an unusal event, and to our knowledge, only four such cases have been reported in the literature. We report a 68-year-old white woman in whom these two diseases were diagnosed concomitantly.
Tadeusz, Robak +6 more
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Rituximab in B-Cell chronic lymphocytic leukemia
Seminars in Oncology, 2003The monoclonal anti-CD20 antibody rituximab exerts its antitumor activity through a variety of mechanisms, including acting against the cellular defects in apoptosis that give rise to B-chronic lymphocytic leukemia (B-CLL). Phase II clinical studies demonstrated that rituximab, given weekly as a single agent, exhibits significantly less activity in B ...
Thomas S, Lin +2 more
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Alemtuzumab in B-Cell Chronic Lymphocytic Leukemia
Clinical Lymphoma, 2004Chronic lymphocytic leukemia (CLL) is the most frequent form of leukemia in the Western hemisphere.1 In this disease, a clonal proliferation of neoplastic B lymphocytes accumulates in bone marrow, blood, lymph nodes, liver, and spleen. According to the World Health Organization (WHO) classification, B-cell CLL is a mature (peripheral) B-cell neoplasm ...
Ilan, Shapira, Michael L, Grossbard
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Histopathology of B-cell chronic lymphocytic leukemia
Hematology/Oncology Clinics of North America, 2004Histologic and immunohistologic findings of B-cell chronic lymphocytic leukemia/small lymphocytic leukemia are revised in the light of the more recent knowledge on the pathobiology of the disease. The guidelines for the optimal handling of the bioptic samples are provided. The relevance of the examination of trephines and surgical specimens is outlined
PILERI, STEFANO +6 more
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The Origin of B-Cell Chronic Lymphocytic Leukemia
Seminars in Oncology, 2006An immunobiologic approach has led to substantial changes in our current view of chronic lymphocytic leukemia (CLL). Several questions remain unsolved and the definition of the cell origin of CLL is still prominent. The presence of somatic mutations of IGHV genes indicates that, at least in a portion of cases, CLL cells had encountered an antigen ...
GHIA , PAOLO PROSPERO +1 more
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