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Richter syndrome in B‐cell chronic lymphocytic leukemia
Pathology International, 2003Richter syndrome (RS) is well known as a secondary high‐grade lymphoma, mostly diffuse large B‐cell lymphoma (DLBCL) developed in patients with B‐cell chronic lymphocytic leukemia (B‐CLL). In this review, we describe clinicopathological, histological, immunophenotypical and genetic findings of RS.
Masafumi Abe, Naoya Nakamura
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11q13 Rearrangement in B Cell Chronic Lymphocytic Leukemia
Leukemia & Lymphoma, 1997Translocation t(11;14)(q13;q32) and/or 11q13 rearrangements have been reported in various B cell immunoproliferative disorders. They appear to be frequent in mantle cell zone lymphoma (MZL) and rare in B-cell chronic lymphocytic leukemia (B-CLL). Discrimination between MZL and B-CLL is sometimes uncertain on the basis of morphology and immunophenotype.
Françoise Brizard+4 more
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ATM mutations in B-cell chronic lymphocytic leukemia.
Cancer research, 1999Mutations in the ATM gene located on the long arm of chromosome 11 at 11q22-23 cause ataxia-telangiectasia, an autosomal recessive disorder that is associated with increased incidence of malignancy and, particularly, lymphoid tumors. A role for ATM in the development of sporadic T-cell chronic leukemias is supported by the finding of loss of ...
F. Bullrich+9 more
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Chromosome studies in stimulated lymphocytes of B‐Cell chronic lymphocytic leukemias
Hematological Oncology, 1983AbstractUsing a sister chromatid differentiation technique, cell cycle study of stimulated lymphocytes of B‐Cell chronic lymphocytic leukemia (B‐CLL) revealed their cell cycle progression to be similar to that of normal lymphocytes stimulated by T‐cell and various polyclonal B‐cell activators (PBA).
Tin Han+4 more
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E Rosette Formation in B Cell Chronic Lymphocytic Leukemia
Acta Haematologica, 1992We describe a patient with B cell chronic lymphocytic leukemia whose B lymphocytes showed the capacity to form rosettes with sheep red blood cells during prolymphocytoid transformation of the disease. In this case, rosette formation was found to be related to the presence of the classic E rosette receptor since the leukemic cells were recognized by the
MUSOLINO, Caterina+7 more
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The cellular biology of B-cell chronic lymphocytic leukemia
Critical Reviews in Oncology/Hematology, 1998In conclusion, B-CLL cells through their immunophenotype have the functional potential required to interact with cells in what has been called the immunological synapse, i.e. the cognate interactions between T-cells, antigen-presenting cells and B-cells during immunopoiesis.
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Small B-cell lymphocytic lymphoma and chronic lymphocytic leukemia
2017A 72-year-old man with a history of diabetes mellitus, hypertension, and hypercholesterolemia self-palpated a left submandibular lump in 2012. Complete blood count (CBC) in his internist’s office showed solitary leukocytosis (white count 22) with predominant lymphocytes for which he was referred to a hematologist.
Steven T. Rosen, Tanya Siddiqi
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i(12q) in B-cell chronic lymphocytic leukemia
Cancer Genetics and Cytogenetics, 1990Tin Han+5 more
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Chromosomal aberrations in chronic B-cell lymphocytic leukemia
Cancer Genetics and Cytogenetics, 1982Karl-Henrik Robèrt, Gösta Gahrton
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Karyotypic evolution of chronic lymphocytic leukemia B cells
Cancer Genetics and Cytogenetics, 1986T. Ghose+3 more
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