Results 211 to 220 of about 713,469 (335)

Blood signals: from birth to disease and death

open access: yes, 2014
Bowman, T.   +6 more
core   +1 more source

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

Exploratory high-throughput screening of repurposed drugs for canine lymphoid malignancies. [PDF]

open access: yesBMC Vet Res
Nishida M   +7 more
europepmc   +1 more source

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome.

open access: yesNew England Journal of Medicine, 2001
B. Druker   +7 more
semanticscholar   +1 more source

CTCF Is Essential for the Development and Maintenance of CALM‐AF10‐Induced Leukemia

open access: yesCancer Science, EarlyView.
CTCF regulates TGM2 gene expression by modulating key histone modifications, including increased acetylation of H3K27 (H3K27ac) and trimethylation of H3K4 (H3K4me3), along with decreased trimethylation of H3K27 (H3K27me3). These epigenetic changes are critical for maintaining the stem‐like properties of CALM‐AF10‐induced AML. Pharmacological inhibition
Yoko Kuroki   +5 more
wiley   +1 more source

Correction for: Accelerated chronic lymphocytic leukemia - characteristics and retrospective analysis of the Polish Adult Leukemia Study Group. [PDF]

open access: yesContemp Oncol (Pozn)
Sośnia O   +22 more
europepmc   +1 more source

ZNF282 Promotes Colorectal Cancer Progression Possibly via E2F1 Activation

open access: yesCancer Science, EarlyView.
ZNF282 is a zinc finger protein overexpressed in colorectal cancer that facilitates tumor progression by promoting cell cycle progression via E2F1 activation. Our study demonstrates that ZNF282 expression is associated with poor prognosis and may serve as a novel prognostic biomarker and therapeutic target. ABSTRACT Colorectal cancer (CRC) is a leading
Tadashi Abe   +23 more
wiley   +1 more source

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