Results 1 to 10 of about 43,548 (209)

Acute Promyelocytic Leukemia in Four Year Old Female Child - A Case Report [PDF]

Journal of Krishna Institute of Medical Sciences University, 2014
Leukemia is the most common malignancy of childhood representing about 30 % of oncohematological diseases diagnosed in children less than 15 years of age.
Anirudha V. Kushtagi, Mihir J. Bhalodia, Mahesh H. Karigoudar, Jyotirling Savle   +3 more
doaj   +2 more sources

Acute Promyelocytic Leukemia Presenting With a Myeloid Sarcoma of the Spine: A Case Report and Literature Review

Frontiers in Oncology, 2022
Myeloid sarcoma is a rare extramedullary tumor of immature myeloid cells. Certain known acute myeloid leukemia cytogenetic abnormalities, in particular t(8,21), has been associated with a higher incidence.
Xuemei Shu, Qiuling Wu, Tao Guo, Hua Yin, Jingdi Liu   +4 more
doaj   +1 more source

Addition of Arsenic Trioxide into Induction Regimens Could Not Accelerate Recovery of Abnormality of Coagulation and Fibrinolysis in Patients with Acute Promyelocytic Leukemia. [PDF]

PLoS ONE, 2016
AIM:All-trans retinoic acid combined to anthracycline-based chemotherapy is the standard regimen of acute promyelocytic leukemia. The advent of arsenic trioxide has contributed to improve the anti-leukemic efficacy in acute promyelocytic leukemia.
Ye Zhang, SiJing Wu, Dan Luo, JianFeng Zhou, DengJu Li   +4 more
doaj   +1 more source

Obesity is a risk factor for acute promyelocytic leukemia: evidence from population and cross-sectional studies and correlation with FLT3 mutations and polyunsaturated fatty acid metabolism

Haematologica, 2020
Obesity correlates with hematologic malignancies including leukemias, but risk of specific leukemia subtypes like acute promyelocytic leukemia and underlying molecular mechanisms are poorly understood.
Luca Mazzarella, Edoardo Botteri, Anthony Matthews, Elena Gatti, Davide Di Salvatore, Vincenzo Bagnardi, Massimo Breccia, Pau Montesinos, Teresa Bernal, Cristina Gil, Timothy J Ley, Miguel Sanz, Krishnan Bhaskaran, Francesco Lo Coco, Pier Giuseppe Pelicci   +14 more
doaj   +1 more source

Treatment of Central Nervous System Relapse in Acute Promyelocytic Leukemia by Venetoclax: A Case Report

Frontiers in Oncology, 2021
Extramedullary relapse of acute promyelocytic leukemia is a rare phenomenon and is associated with a poor prognosis, with the central nervous system being the most common site of relapse. The current treatments are still limited.
Xuzhao Zhang, Jinliang Chen, Weiqin Wang, Xian Li, Yanbin Tan, Xiaohong Zhang, Wenbin Qian   +6 more
doaj   +1 more source

SECONDARY ACUTE PROMYELOCYTIC LEUKEMIA DEVELOPED AFTER TREATMENT OF NON-HODGKIN'S LYMPHOMA. CLINICAL CASE AND REVIEW OF LITERATURE.

Arta Medica, 2020
Background: Acute promyelocytic leukemia is an acute myeloid leukemia that accounts approximately 10% of acute myeloid leukemia cases. Acute promyelocytic leukemias usually appears as a de novo finding.
Victor Tomacinschii, Maria Robu, Vasile Musteață, Irina Mocanu, Sanda Buruiană, Natalia Sporîș, Veronica Feghiu   +6 more
doaj   +1 more source

Molecular methods for genomic analyses of variant PML-RARA or other RARA-related chromosomal translocations in acute promyelocytic leukemia [PDF]

, 2012
TO THE EDITOR: We read an interesting paper by Palta et al. in a recent issue of the Korean Journal of Hematology titled, "ZBTB16-RARA variant of acute promyelocytic leukemia with tuberculosis: a case report and review of literature" [1].
Kim, Min Jin, Marschalek, Rolf, Meyer, Claus, Park, Tae Sung, Yang, John Jeongseok   +4 more
core   +1 more source

The CEBPA gene is down-regulated in acute promyelocytic leukemia and its upstream promoter, but not the core promoter, is highly methylated

Haematologica, 2011
Impairment of CCAAT Enhancer Binding Protein alpha (CEBPA) function is a common finding in acute myeloid leukemia; nevertheless, its relevance for acute promyelocytic leukemia pathogenesis is unclear.
Bárbara Amélia Santana-Lemos, Ana Paula Alencar de Lima Lange, Mariana Tereza de Lira Benício, Thiago Donizete da Silva José, Antônio Roberto Lucena-Araújo, Alexandre Krause, Carolina Hassibe Thomé, Eduardo Magalhães Rego   +7 more
doaj   +1 more source

Severe acute axonal neuropathy following treatment with arsenic trioxide for acute promyelocytic leukemia: a case report [PDF]

, 2016
Peripheral neuropathy is a common complication of arsenic toxicity. Symptoms are usually mild and reversible following discontinuation of treatment. A more severe chronic sensorimotor polyneuropathy characterized by distal axonal-loss neuropathy can be ...
Kuhn, Marcus, Nabergoj, Mithia, Sammartin, Kety, Vianello, Fabrizio   +3 more
core   +3 more sources

A case of acute myeloid leukemia with promyelocytic features characterized by expression of a novel RARG-CPSF6 fusion [PDF]

, 2018
Key Points Novel RARG-CPSF6 fusion in an AML case with promyelocytic features and no evidence of PML-RARA or X-RARA fusion. Gene fusions involving RARG can initiate AML with promyelocytic morphological features.
Duncavage, Eric J., Griffith, Malachi, Griffith, Obi L., Hassan, Anjum, Lee, Yi-Shan, Miller, Christopher A., O\u27Laughlin, Michelle D., Schmidt, Heather, Skidmore, Zachary L., Tian, Ling, Tricarico, Christopher, Uy, Geoffrey L., Wartman, Lukas D., Welch, John S.   +13 more
core   +2 more sources