Results 41 to 50 of about 43,912 (220)

Additional chromosome abnormalities in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy

Haematologica, 2010
Background Acute promyelocytic leukemia is a subtype of acute myeloid leukemia characterized by the t(15;17). The incidence and prognostic significance of additional chromosomal abnormalities in acute promyelocytic leukemia is still a controversial ...
José Cervera, Pau Montesinos, Jesús M. Hernández-Rivas, María J. Calasanz, Anna Aventín, María T. Ferro, Elisa Luño, Javier Sánchez, Edo Vellenga, Chelo Rayón, Gustavo Milone, Javier de la Serna, Concha Rivas, José D. González, Mar Tormo, Elena Amutio, Marcos González, Salut Brunet, Bob Lowenberg, Miguel A. Sanz   +19 more
doaj   +1 more source

Monocyte maturation pattern by flow cytometry expression of CD64, CD300e, and CD14 correlates to presence of myeloid neoplasm and helps identify blast equivalents in the setting of monocytic neoplasm

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract CD300e is a marker of mature monocytes in flow cytometry; however, there is limited detailed information on staining patterns in conjunction with other monocyte markers. We evaluated the flow cytometric staining patterns of CD64, CD14, and CD300e in 12 negative and 33 positive peripheral blood specimens and 16 negative and 56 positive bone ...
Jenny Zhang, Jacob Kaplan, Elizabeth Courville   +2 more
wiley   +1 more source

Relapse as hypogranular morphologic subtype in classic acute promyelocytic leukemia [PDF]

Romanian Journal of Medical Practice, 2016
We present the case of patient who had morphologically different cells (atypical promyelocytic) when disease relapse, which led to the establishment of two diagnoses. The final diagnosis was of acute promyelocytic leukemia – hipogranular form.
Tatiana Cristina ENACHE, Ana-Maria VLĂDĂREANU, Mădălina BEGU, Horia BUMBEA   +3 more
doaj   +1 more source

The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients [PDF]

, 2001
Background and Objectives. Detection of PML-RAR alpha transcripts by RT-PCR is now established as a rapid and sensitive method for diagnosis of acute promyelocytic leukemia (APL), Although the majority of patients in longterm clinical remission are ...
Carrara, P, de Sousa, AB, Diamond, J, Foroni, L, Gameiro, P, Guimaraes, JE, Hoffbrand, AV, Mehta, AB, Parreira, A, Prentice, HG, Silva, AL, Vieira, S   +11 more
core  

Measurable residual disease by multicolor flow cytometry in acute myeloid leukemia: A comparison of peripheral blood and bone marrow

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Measurable residual disease (MRD) monitoring by multiparameter flow cytometry (MFC) is well established in bone marrow (BM) samples for acute myeloid leukemia (AML), but its use in peripheral blood (PB) remains less developed. We adapted a semi‐automated and well validated MFC‐MRD assay, originally developed for BM, to PB aiming to evaluate ...
Jonas Schadt, Malte von Bonin, Uta Oelschlägel, Christoph Röllig, Christian Thiede, Leo Ruhnke, Martin Bornhäuser, Sebastian Brenner, Maximilian Alexander Röhnert   +8 more
wiley   +1 more source

Multiple acute ischemic strokes as the onset manifestation of acute promyelocytic leukemia

Romanian Journal of Internal Medicine, 2018
Acute promyelocytic leukemia often manifests with hemorrhagic diathesis, thrombotic events being much rarer. This is the case of a 59-year-old patient with thrombotic cerebro-vascular complications as the onset manifestation of acute promyelocytic ...
Manea Maria Mirabela, Dobri Ana Maria, Dragoş Dorin, Borsaru Gabriela, Tuţă Sorin   +4 more
doaj   +1 more source

First reported case of pneumonia caused by Cedecea lapagei in America

Brazilian Journal of Infectious Diseases, 2013
Cedecea represents a genus in the Enterobacteriaceae family that has been rarely associated with human infection. The clinical relevance of Cedecea lapagei has yet to be elucidated. This is the first reported case of pneumonia due to C.
Luis Antonio Sanchez Lopez, Bárbara Saenz Ibarra, Jess Alberto Cárdenas de la Garza, Felipe de Jesus Martin Perez Rada, Ana Isabel Sepúlveda Nuñez, María Guadalupe Rodríguez López   +5 more
doaj   +1 more source

Detection of monosomy 7 in interphase cells of patients with myeloid disorders [PDF]

, 1990
Six patients, five with acute myeloid leukemia (AML) and one with a myelodysplastic syndrome (MDS), were found to have monosomy 7 by conventional cytogenetics at diagnosis.
Cremer, Thomas, Gezer, Sefer, Kolluri, Rukmini V., Manuelidis, L., Raza, Azra, Sait, Sheila   +5 more
core   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

An Unusual Coexistence of Primary Central Nervous System Non-Hodgkin’s Lymphoma and Acute Promyelocytic Leukemia

Case Reports in Hematology, 2018
Acute promyelocytic leukemia and primary central nervous system lymphoma are uncommon hematological malignancies. The co-occurrence of acute myeloid leukemia with various lymphoproliferative diseases is an extremely rare condition, especially in the ...
Nicola Stefano Fracchiolla, Mariarita Sciumè, Giulia Cernuschi, Agostino Cortelezzi   +3 more
doaj   +1 more source