Results 101 to 110 of about 1,571,497 (188)

Retinoic Acid and Arsenic Trioxide sensitize Acute Promyelocytic Leukemia cells to ER stress

, 2017
Promyelocytic leukemia (APL) is characterized by the chromosomal translocation t(15:17) that results in the expression of the chimeric protein PML-RARα. The fusion of PML, a tumor suppressor that is the major component of the PML-nuclear bodies, with the
FAZI, Francesco, Divona, Mariadomenica, MASCIARELLI, SILVIA, Ottone, Tiziana, Lo Coco Francesco,, Noguera, Nelida, CAPUANO, ERNESTINA, DE PANFILIS, SIMONE   +7 more
core  

Acute Promyelocytic Leukemia - 2

, 2018
An image from a bone marrow smear demonstrating numerous myeloid precursors arrested at the promyelocyte stage, and cells with bundles of auer rods known as faggot cells in a patient with acute promyelocytic leukemia (50X oil immerson)
To, Michelle, Kwon, Gloria
core   +1 more source

M3/M3v acute non lymphocytic leukemia (M3-ANLL) - M3/M3v acute myeloid leukemia (AML M3/M3v) - Acute promyelocytic leukemia (APL) [PDF]

, 2006
Review on M3/M3v acute non lymphocytic leukemia (M3-ANLL) - M3/M3v acute myeloid leukemia (AML M3/M3v) - Acute promyelocytic leukemia (APL), with data on clinics, and the genes ...
C Schoch, Schoch, C
core   +1 more source

Metaphase and Interphase Cytogenetics with Alu-PCR-amplified Yeast Artificial Chromosome Clones Containing the BCR Gene and the Protooncogenes c-raf-1, c-fms, and c-erbB-21 [PDF]

, 1992
A human yeast artificial chromosome (YAC) library was screened by polymerase chain reaction with oligonucleotide primers defined for DNA sequences of the BCR gene and the protooncogenes c-raf-1, c-fms, and c-erB-2.
Olson, Maynard V., Riethman, Harold C., Speicher, Michael R., Cremer, Thomas, Green, Eric D., Becher, Reinhard, Konecki, David, Taniwaki, Masafumi, Lengauer, Christoph   +8 more
core   +1 more source

Acute Promyelocytic Leukemia Complicated by Deep Venous Thrombosis, Pulmonary Thromboembolism, and Hematemesis

Indian Journal of Clinical Cardiology
Acute promyelocytic leukemia (APML) is a myeloid leukemia classified as M3-AML. It is known for its bleeding diathesis, which is predominantly driven by disseminated intravascular coagulation and primary hyperfibrinolysis.
Sudipta Mondal, Saurav Banerjee
doaj   +1 more source

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

Advanced Science, Volume 13, Issue 50, 7 September 2026.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun, Bo Jia, Jiahui Shi, Shuang Li, Guo Bao, Dong Bian, Kai Chen, Junlong Tan, Xuenan Gu, Yan Guan, Yu Qin, Xinhua Qu, Xiaogang Wang, Yufeng Zheng, Hongtao Yang   +14 more
wiley   +1 more source

Detection of monosomy 7 in interphase cells of patients with myeloid disorders [PDF]

, 1990
Six patients, five with acute myeloid leukemia (AML) and one with a myelodysplastic syndrome (MDS), were found to have monosomy 7 by conventional cytogenetics at diagnosis.
Cremer, Thomas, Manuelidis, L., Sait, Sheila, Raza, Azra, Kolluri, Rukmini V., Gezer, Sefer   +5 more
core   +1 more source

Allogeneic stem cell transplantation for advanced acute promyelocytic leukemia in the ATRA and ATO era

Haematologica, 2012
The role of allogeneic stem cell transplant in advanced acute promyelocytic leukemia patients who received standard first- and second-line therapy is still unknown.
Safaa M. Ramadan, Ambra Di Veroli, Agnese Camboni, Massimo Breccia, Anna Paola Iori, Franco Aversa, Luca Cupelli, Cristina Papayannidis, Andrea Bacigalupo, William Arcese, Francesco Lo-Coco   +10 more
doaj   +1 more source

UBE2O Drives Immune Evasion and Radioimmunotherapy Resistance in Lung Cancer by Degrading CDKL1 to Induce PD‐L1 Transcription

Advanced Science, Volume 13, Issue 52, 18 September 2026.
UBE2O targets CDKL1 for the degradation to upregulate PD‐L1 expression and promotes resistance to radioimmunotherapy in lung cancer, supporting the potential of targeting UBE2O as a promising therapeutic strategy. ABSTRACT Resistance to radioimmunotherapy is one of the primary causes of treatment failure in lung cancer patients; however, the underlying
Huichan Xue, Xiaohua Jie, Zhiwei Liu, Ruoxin Fang, Shuo Wu, Xiaorong Dong, Shuangbing Xu   +6 more
wiley   +1 more source

Acute lower limb ischemia revealing hypo granular acute promyelocytic leukemia

Leukemia Research Reports
Introduction: Acute promyelocytic leukemia (AML-M3), classified as acute Myeloid leukemia with PML RARA according to the 5th edition of the World Health Organization classification of haematolymphoid tumors 2022 [1], is marked by abnormal promyelocyte ...
Sabrina Belmahi, Zainab Kajeiou, Loubna Yacoubi, Noussaiba Azzi, Mounia Slaoui, Abdelilah Berhili, Mohammed Bensalah, Rachid Seddik   +7 more
doaj   +1 more source