Results 251 to 260 of about 1,294,431 (344)

Acute myeloid leukemias with ring sideroblasts show a unique molecular signature straddling secondary acute myeloid leukemia and de novo acute myeloid leukemia

Haematologica, 2017
Pedro Martin-Cabrera, Sabine Jeromin, Karolína Perglerovà, Claudia Haferlach, Wolfgang Kern, Torsten Haferlach   +5 more
doaj   +1 more source

Dual targeting of tumoral cells and immune microenvironment by blocking the IL-33/IL1RL1 pathway. [PDF]

Nat Commun
Fu D, Jiang H, Long A, Harris E, Guo H, Capitano ML, Wrangle J, Faust JR, Gopalakrishnapillai A, Pasupuleti SK, Ramdas B, Kapur R, Barwe SP, Cheung NV, Paczesny S.   +14 more
europepmc   +1 more source

Cryo‐Inactivated Cancer Cells Derived Magnetic Micromotors for Tumor Immunotherapy

Advanced Science, EarlyView.
Cryo‐inactivated cancer cell‐based magnetic micromotors are developed for synergistic tumor immunotherapy via magnetic targeting. These micromotors can induce ferroptosis and immunogenic cell death, deliver tumor antigens, and activate the Mn2+‐dependent cGAS‐STING pathway. The system effectively suppresses tumor progression, recurrence, and metastasis,
Qingfei Zhang, Gaizhen Kuang, Wenzhao Li, Yuanjin Zhao   +3 more
wiley   +1 more source

Phase I/II clinical trial on the safety and preliminary efficacy of donor-derived anti-leukemia cytotoxic T lymphocytes for the prevention of leukemia relapse in children given haploidentical hematopoietic stem cell transplantation: study rational and design. [PDF]

Front Immunol
Montagna D, Comoli P, Tanzi M, Montini E, Moretta A, Taurino G, Boghen S, Panigari A, Mina T, Giorgiani G, Del Fante C, Perotti C, Zecca M.   +12 more
europepmc   +1 more source

A ROS‐Responsive Dual‐Targeting Drug Nanocarrier Serving as a GSI Synergist and Ferroptosis Sensitizer for T‐Cell Acute Lymphoblastic Leukemia

Advanced Science, EarlyView.
A self‐assembling nanotherapeutic strategy is designed—CD38‐PHD/G‐NPs, which released γ‐secretase inhibitor first, followed by adaptive dihydroartemisnin release in response to elevated reactive oxygen species levels. This controlled, sequential release strategy maximizes the synergistic anti‐leukemic efficacy of two agents with distinct mechanisms of ...
Ruinan Jia, Yang Liu, Jilong Xiao, Yuan Xia, Xin Zhao, Huixian Ma, Jingjing Ye, Zhiyue Zhang, Tao Sun, Chunyan Ji   +9 more
wiley   +1 more source

AKI in chronic myeloid leukemia: remember lysozyme-induced nephropathy. [PDF]

J Bras Nefrol
Santos A, Marques N, Pestana R.
europepmc   +1 more source

Commensal Viruses Promote Intestinal Stem Cell Regeneration Following Radiation Damage by Inhibiting Hyperactivation of RIG‐I and Notch Signals

Advanced Science, EarlyView.
Ionizing radiation disrupts gut virome and bacteriome. Gut commensal viruses protect against intestinal damage and promote stem cell regeneration by inhibiting hyperactivation of RIG‐I and Notch signaling in stem cells. Fecal virome transplantation (FVT) from healthy donors can serve as a potential therapeutic intervention by enriching phages targeting
Xiaotong Zhao, Yu Cai, Yujia Hou, Yanjin Wu, Tingting Wei, Lili Li, Zhaojun Duan, Xinran Lu, Jiahui Meng, Haitao Zhou, Qin Wang, Jinhan Wang, Chang Xu, Liqing Du, Saijun Fan, Feng Wang, Qiang Liu, Yang Liu   +17 more
wiley   +1 more source

5q deletion in childhood T-acute lymphoblastic leukemia at diagnosis: a case report. [PDF]

J Med Case Rep
Sbibih Y, Bensalah M, Slaoui M, Saddari A, Trougouty N, Berhili A, Seddik R.   +6 more
europepmc   +1 more source

Nanomaterials Trigger Functional Anti‐Tumoral Responses in Primary Human Immune Cells

Advanced Science, EarlyView.
Nanoparticles are used to improve immunomodulatory therapies, but the impact of drug‐free nanomaterials on the immune system remains unknown. Screening common biomedical nanoparticles (NPs) reveals that PLGA NPs enhanced NK cell anti‐tumoral activity and transcriptional activation in human NK and pan T cells.
Vincent Mittelheisser, Olivier Lefebvre, Mainak Banerjee, Shayamita Ghosh, Amandine Dupas, Marie‐Charlotte Diringer, Juliette Blumberger, Louis Bochler, Sébastien Harlepp, Annabel Larnicol, Angélique Pichot, Tristan Stemmelen, Anne Molitor, Chloé Moritz, Christine Carapito, Raphaël Carapito, Loïc J. Charbonnière, François Lux, Olivier Tillement, Jacky G. Goetz, Alexandre Detappe   +20 more
wiley   +1 more source

RETRACTED: Kalicińska et al. Pneumonia in Patients with Chronic Lymphocytic Leukemia Treated with Venetoclax-Based Regimens: A Real-World Analysis of the Polish Adult Leukemia Group (PALG). <i>Cancers</i> 2024, <i>16</i>, 4168. [PDF]

Cancers (Basel)
Kalicińska E, Jabłonowska-Babij P, Morawska M, Iskierka-Jażdżewska E, Drozd-Sokołowska J, Paszkiewicz-Kozik E, Szukalski Ł, Strzała J, Gosik U, Dębski J, Andrasiak I, Skotny A, Jamroziak K, Wróbel T.   +13 more
europepmc   +1 more source