Results 41 to 50 of about 4,728,853 (203)

Cytoplasmic LIF reprograms invasive mode to enhance NPC dissemination through modulating YAP1-FAK/PXN signaling

Nature Communications, 2018
Molecular pathways regulating nasopharyngeal carcinoma (NPC) metastasis are unclear. Here they report higher levels of cytoplasmic leukemia inhibitory factor (cLIF) and LIF receptor (LIFR) to correlate with higher metastasis in NPC patients, and show ...
Shu-Chen Liu, Tien Hsu, Yu-Sun Chang, An-Ko Chung, Shih Sheng Jiang, Chun-Nan OuYang, Chiou-Hwa Yuh, Chuen Hsueh, Ya-Ping Liu, Ngan-Ming Tsang   +9 more
doaj   +1 more source

No correlation between pinopode formation and LIF and MMP2 expression in endometrium during implantation window

Folia Histochemica et Cytobiologica, 2012
Implantation depends on two factors — embryo and endometrium. The period of maximal endometrial receptivity is a poorly understood phenomenon.
Przemysław Wirstlein, Jana Skrzypczak, Mateusz Mikołajczyk   +2 more
doaj   +1 more source

Concentrations of serum leukemia inhibitory factor (LIF) in patients with hematologic malignances [PDF]

Leukemia, 1997
Concentrations of serum leukemia inhibitory factor (LIF) in patients with hematologic ...
V, Lorgeot, V, Praloran, P, Turlure, Y, Denizot   +3 more
openaire   +2 more sources

LIF Mediates Proinvasive Activation of Stromal Fibroblasts in Cancer

Cell Reports, 2014
Signaling crosstalk between tumor cells and fibroblasts confers proinvasive properties to the tumor microenvironment. Here, we identify leukemia inhibitory factor (LIF) as a tumor promoter that mediates proinvasive activation of stromal fibroblasts ...
Jean Albrengues, Isabelle Bourget, Catherine Pons, Vincent Butet, Paul Hofman, Sophie Tartare-Deckert, Chloe C. Feral, Guerrino Meneguzzi, Cedric Gaggioli   +8 more
doaj   +1 more source

Leukemia inhibitory factor in rat fetal lung development: expression and functional studies. [PDF]

PLoS ONE, 2012
BACKGROUND: Leukemia inhibitory factor (LIF) and interleukin-6 (IL-6) are members of the family of the glycoprotein 130 (gp130)-type cytokines. These cytokines share gp130 as a common signal transducer, which explains why they show some functional ...
Cristina Nogueira-Silva, Paulina Piairo, Emanuel Carvalho-Dias, Francisca O Peixoto, Rute S Moura, Jorge Correia-Pinto   +5 more
doaj   +1 more source

Effect of Irisin on LIF and integrin αvβ3 in rats of implantation failure

Reproductive Biology and Endocrinology, 2021
Objective The aim of this study is to investigate the effect of irisin on leukemia inhibitory factor (LIF) and integrin αvβ3 in implantation failure uterus.
Li Zhou, Chenggang Li, Xiangshu Liu, Tao Zhang   +3 more
doaj   +1 more source

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

Effect of tumor primary culture (TPC) conditioned medium (CM) and leukemia inhibitory factor (LIF)-neutralizing antibody

, 2011
Copyright information:Taken from "Mouse mammary tumors display Stat3 activation dependent on leukemia inhibitory factor signaling"http://breast-cancer-research.com/content/9/5/R69Breast cancer research : BCR 2007;9(5):R69-R69.Published online 10 Oct ...
Ana Quaglino (40760), Edith C Kordon (40764), Roberto P Meiss (40763), Carolina Schere-Levy (40761), Leonardo Romorini (40762)   +4 more
core   +1 more source

Chemical Screening Identifies Danofloxacin as a Self‐Renewal Agonist of Embryonic Stem Cells through Alleviation of HDAC1‐Mediated Deacetylation of Tert and Prdm10

Advanced Science, EarlyView.
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang, Junxiang Ji, Baoxing Dong, Zhenhua Zhu, Xucheng Lv, Peng Chen, Wenqiang Liu, Min Zhou, Shou‐Dong Ye   +8 more
wiley   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source