Results 91 to 100 of about 155,017 (308)

Array CGH in Human Leukemia: From Somatics to Genetics

, 2011
During the past decade, array CGH has been applied to study copy number alterations in the genome in human leukemia in relation to prediction of prognosis or responsiveness to therapy.
A. Buijs, L.T. van der Veken
core   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Understanding infectious complications in patients with lower risk myelodysplastic syndromes: a step towards improving survival

Haematologica
Not available.
Guillermo Garcia-Manero
doaj   +1 more source

Segmentation of White Blood Cell from Acute Lymphoblastic Leukemia Images Using Dual-Threshold Method [PDF]

, 2016
We propose a dual-threshold method based on a strategic combination of RGB and HSV color space for white blood cell (WBC) segmentation. The proposed method consists of three main parts: preprocessing, threshold segmentation, and postprocessing.
Yao, Di, Li, Yan, Mi, Lei, Cao, Yihui, Zhu, Rui   +4 more
core   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Inhibition of menin, BCL-2, and FLT3 combined with a hypomethylating agent cures NPM1/FLT3-ITD/-TKD mutant acute myeloid leukemia in a patient-derived xenograft model

Haematologica, 2023
Bing Z. Carter, Po Yee Mak, Wenjing Tao, Lauren B. Ostermann, Duncan H. Mak, Baozhen Ke, Peter Ordentlich, Gerard M. McGeehan, Michael Andreeff   +8 more
doaj   +1 more source

Anesthesiologic management of cesarean section at 35-weeks pregnancy with acute myeloid leukemia and profound thrombocytopenia refractory to platelet transfusion: A case report

Journal of Obstetric Anaesthesia and Critical Care, 2020
Leukemia is a very rare condition in pregnancy. The pathology itself poses a great challenge to the anesthesiologist due to the inherent risks such as blast crisis, tumor lysis syndrome, anemia, and thrombocytopenia.
Jemea Bonaventure, Berinyuy Nyuydzefon Emelinda, Iroume Cristella Raïssa Bifouna, Esiene Agnes   +3 more
doaj   +1 more source

Sleep Disturbances in Survivors of Childhood Acute Lymphoblastic Leukemia: A Cross-Sectional Study

Indian Pediatrics
Survivors of childhood cancer are at risk of sleep disturbances, an often, neglected aspect of holistic health. This study was carried out to determine the prevalence of sleep disturbances in survivors of pediatric acute lymphoblastic leukemia (ALL) and to identify any risk factors for the same.Survivors of ALL aged 6-18 years, who had completed their ...
Kanwaljeet Kaur Chopra, Aditya Kumar Gupta, Jagdish Prasad Meena, Biswaroop Chakrabarty, Rajesh Sagar, Ravindra Mohan Pandey, Rachna Seth   +6 more
openaire   +2 more sources

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Evaluating measurable residual disease in acute myeloid leukemia

Blood Advances, 2018
: Mounting evidence indicates that the presence of measurable (“minimal”) residual disease (MRD), defined as posttherapy persistence of leukemic cells at levels below morphologic detection, is a strong, independent prognostic marker of increased risk of ...
Farhad Ravandi, Roland B. Walter, Sylvie D. Freeman   +2 more
doaj   +1 more source