Results 51 to 60 of about 112,142 (249)

Possible immunoenhancement of persistent viremia by feline leukemia virus envelope glycoprotein vaccines in challenge-exposure situations where whole inactivated virus vaccines were protective. [PDF]

open access: yes, 1986
Kittens immunized with purified native FeLV-gp70 or -gp85 envelope proteins developed ELISA, but not virus neutralizing, antibodies in their serum to both whole FeLV and FeLV-gp70.
Birch, D   +3 more
core  

Bovine Leukemia Virus Involvement In Enzootic Bovine Leukosis

open access: yes, 1978
Publisher Summary Enzootic bovine leukosis is a contagious disease induced by bovine leukemia virus (BLV). It is a chronic disease that develops over a long period and can be schematically divided into three phases: (1) from birth to infection (some animals are already infected at birth), (2) from viral infection to tumorous transformation (a number ...
Burny, Arsène   +10 more
openaire   +3 more sources

Single‐Cell Dissection Reveals Immune Dysregulation After CD5 or CD7‐Directed Chimeric Antigen Receptor T‐Cell Therapy

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA/TCR/BCR sequencing reveals that 5CAR therapy in T‐ALL induces T‐cell exhaustion, reduces EBV‐associated TCRs, lowers TCR/BCR diversity, and increases NK/DC/monocyte activation and function. In contrast, 7CAR therapy reduces multiple pathogen‐associated TCRs, enhances NK cell activation and function, decreases monocyte activation, and ...
Yuechen Luo   +12 more
wiley   +1 more source

Terminal deoxynucleotidyltransferase. Serological studies and radioimmunoassay [PDF]

open access: yes, 1976
Mouse antisera against calf terminal deoxynucleotidyltransferase (terminal transferase) have been prepared. The sera have been used to characterize terminal transferase both by studying inhibition of enzyme activity and by developing a competition ...
Baltimore, David   +2 more
core  

Safety and Efficacy of Adoptive Transfer of Stem Cell Memory Enriched Virus Specific T Cells against CMV and EBV

open access: yesAdvanced Science, EarlyView.
This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao   +13 more
wiley   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

open access: yesXenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

MODERN METHODS AND EXPERIENCE OF STRUGGLE AGAINST LEUKEMIA OF CATTLE

open access: yesВ мире научных открытий, 2018
The article presents the main methods of diagnosis and control of the bovine leukemia virus currently used. The wide spread of the disease is due to a fairly easy transmission of the virus, the lack of early diagnosis, vaccination and treatment ...
Tatyana Vladimirovna Zubova   +2 more
doaj   +1 more source

Effect of BLV Infection on the Immune Function of Polymorphonuclear Neutrophil in Dairy Cows

open access: yesFrontiers in Veterinary Science, 2021
Enzootic bovine leukemia is a late-onset, neoplastic infection caused by the bovine leukemia virus (BLV). BLV infection hinders the function of the immune system and induces other diseases, which negatively affects the performance and health of the ...
Guanxin Lv   +9 more
doaj   +1 more source

Bovine Leukemia Virus Infection and Mastitis

open access: yesJournal of Dairy Science, 1982
Adult dairy cows (226 head) in three herds were sampled both for bovine leukemia virus infection and for mastitis infection. A chi square analysis revealed no statistically significant association between the two types of infection.
J, Fetrow, J F, Ferrer
openaire   +2 more sources

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

open access: yesAdvanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa   +23 more
wiley   +1 more source

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