Panton-Valentine Leukocidin–Positive MRSA, Shanghai
To the Editor: The development of methicillin resistance in community strains of Staphylococcus aureus is a notable step in the evolution of this pathogen. Unlike their equivalents in the hospital environment, community-associated methicillin-resistant S.
Li-Zhong Han +7 more
openaire +4 more sources
Staphylococcus aureus is a formidable human pathogen that uses secreted cytolytic factors to injure immune cells and promote infection of its host. Of these proteins, the bicomponent family of pore-forming leukocidins play critical roles in S.
D. Balasubramanian +11 more
semanticscholar +3 more sources
Skin Infections Caused by Panton-Valentine Leukocidin and Methicillin-Susceptible Staphylococcus aureus in Child, Japan. [PDF]
We describe a pediatric case of recurrent skin infections caused by a Panton-Valentine leukocidin and exfoliative toxin E double-positive methicillin-susceptible Staphylococcus aureus clonal complex 188 clone.
Shoji K +11 more
europepmc +2 more sources
OBJECTIVES Panton-Valentine leukocidin (PVL) gene (lukS/F-PV)-positive community-acquired methicillin-resistant Staphylococcus aureus (MRSA), particularly the USA300 clone, is a health concern worldwide. Recently, community-acquired MRSA clones have been
S. Takadama +5 more
semanticscholar +3 more sources
The Relative Importance of Cytotoxins Produced by Methicillin-Resistant Staphylococcus aureus Strain USA300 for Causing Human PMN Destruction. [PDF]
Staphylococcus aureus (S. aureus) is a prominent Gram-positive bacterial pathogen that expresses numerous cytotoxins known to target human polymorphonuclear leukocytes (PMNs or neutrophils).
Nygaard TK +7 more
europepmc +2 more sources
Panton-Valentine Leukocidin Genes inStaphylococcus aureus
The pathogenicity of Staphylococcus aureus depends on various bacterial surface components and extracellular proteins. However, the precise role of single virulence determinants in relation to infection is hard to establish. The frequent recovery of staphylococcal isolates that produce leukocidal toxins from patients with deep skin and soft tissue ...
Melles, Damian +5 more
openaire +5 more sources
Panton-Valentine Leukocidin–positiveStaphylococcus aureus, Singapore
To the Editor: Necrotizing community-acquired pneumonia attributable to Panton-Valentine leukocidin–producing strains of Staphylococcus aureus has been described as a distinct clinical syndrome with a high death rate in young, immunocompetent patients (1,2). This letter details the first reported case of necrotizing pneumonia caused by Panton-Valentine
Li-Yang Hsu +5 more
openaire +3 more sources
Panton-valentine leukocidin and staphyloccoccal skin infections in schoolchildren.
The Panton-Valentine leukocidin is associated with staphylococcal skin and pulmonary infections. We describe a school outbreak of skin infections and the public health response to it. Nasal carriage of a Panton-Valentine leukocidin-positive Staphylococcus aureus clone was detected only in previously ill classmates and their family members.
Boubaker, K. +6 more
openaire +5 more sources
Characterization and Comparison of 2 Distinct Epidemic Community-Associated Methicillin-Resistant Staphylococcus aureus Clones of ST59 Lineage. [PDF]
Sequence type (ST) 59 is an epidemic lineage of community-associated (CA) methicillin-resistant Staphylococcus aureus (MRSA) isolates. Taiwanese CA-MRSA isolates belong to ST59 and can be grouped into 2 distinct clones, a virulent Taiwan clone and a ...
A Bera +55 more
core +26 more sources
Panton-Valentine Leukocidin-Positive Staphylococcus aureus in Family and Pet Cat. [PDF]
Continued detection of Panton-Valentine leukocidin–positive Staphylococcus aureus in samples from a family with severe repeated skin infections and their pet cat suggests transmission between the family and the cat.
Bethe A +12 more
europepmc +2 more sources

