Results 71 to 80 of about 17,148 (192)

Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications

Journal of Periodontal Research, EarlyView.
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu, Yuan Chen, Mario Romandini, Håvard Jostein Haugen, Sašo Ivanovski   +4 more
wiley   +1 more source

Human blood granulocyte degranulation and lysis intensity during interaction with Yersinia pestis in the ex vivo model of bacteriemia

Журнал микробиологии, эпидемиологии и иммунобиологии
Introduction. Considering the decisive role of antibacterial strategies of secretory degranulation and NETosis in the prevention of sepsis, it is of interest to study the interaction of Yersinia pestis with human blood granulocytes using an ex vivo ...
Aleksandr L. Kravtsov, Svetlana A. Bugorkova, Svetlana N. Klyueva, Tatyana P. Shmelkova, Vitaly A. Kozhevnikov   +4 more
doaj   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Absence of Elastase in Human and Rabbit Leukocytes*

Journal of Investigative Dermatology, 1967
Histological sections of inflammatory tissues frequently show loss of elastic tissue staining (1). With one exception (2), however, there has been no demonstration of a mammalian elastase outside of the pancreas (3). Tissues that have been subjected to such treatment as irradiation, freeze-thawing, burning, and other types of trauma known to cause ...
Chotiner, Gerald, Smith, J. Graham, Rosett, Theodore   +2 more
openaire   +1 more source

Secretory leukocyte protease inhibitor in punch biopsies from human colonic mucosa

Mediators of Inflammation, 2001
Secretory leukocyte protease inhibitor (SLPI) is a wellknown protease inhibitor. Its function is thought to be protease/protease-inhibitor balance. Free proteolytic activity, mainly pancreatic elastase, anionic trypsin and granulocytic elastase, has been
Max Nyström, Ulla Peterson Westin, Carina Linder, Kjell Ohlsson   +3 more
doaj   +1 more source

Spartinoxide, a New Enantiomer of A82775C with Inhibitory Activity toward HLE from the Marine-derived Fungus

Natural Product Communications, 2010
The fungus Phaeosphaeria spartinae is an endophyte of the marine alga Ceramium sp. Investigation of this marine-derived fungus led to the isolation of spartinoxide ( 1 ), which is the enantiomer of the known compound A82775C ( 2 ).
Mahmoud Fahmi Elsebai, Stefan Kehraus, Michael Gütschow, Gabriele M. König   +3 more
doaj   +1 more source

Neutrophil elastase in cervical fluid in women with short cervical length

Taiwanese Journal of Obstetrics & Gynecology, 2018
Objective: The aim of the study was to determine the relationships between short cervical length (CL) and levels of cervical fluid neutrophil elastase (NE), secretory leukocyte protease inhibitor (SLPI), and interleukin 8 (IL-8) in the second trimester ...
Soo Ran Choi, Soon-Sun Hong, Juyoung Kim, Keun-Young Lee   +3 more
doaj   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Mucosal Progranulin expression is induced by H. pylori, but independent of Secretory Leukocyte Protease Inhibitor (SLPI) expression

BMC Gastroenterology, 2011
Background Mucosal levels of Secretory Leukocyte Protease Inhibitor (SLPI) are specifically reduced in relation to H. pylori-induced gastritis. Progranulin is an epithelial growth factor that is proteolytically degraded into fragments by elastase (the ...
Treiber Gerhard, Schindele Daniel, Schönberg Cornelius, Kuester Doerthe, Wex Thomas, Malfertheiner Peter   +5 more
doaj   +1 more source

Biological definition of periodontal diseases: A historical review of host‐response diagnostics and their implications for disease classification

Periodontology 2000, EarlyView.
Abstract Background Understanding periodontal diseases through a biological lens has been a central aim in periodontal research. Visionary pioneers in the field established the foundations of our knowledge, providing invaluable insights into disease mechanisms and progression.
Nagihan Bostanci, Melissa M. Grant, Moritz Kebschull   +2 more
wiley   +1 more source