Results 1 to 10 of about 8,876 (143)

Association Between Weight Change and Leukocyte Telomere Length in U.S. Adults

Frontiers in Endocrinology, 2021
ObjectiveTo investigate the association of dynamic weight change in adulthood with leukocyte telomere length among U.S. adults.MethodsThis study included 3,886 subjects aged 36-75 years from the National Health and Nutrition Examination Survey (NHANES ...
Yiling Zhang, Yiling Zhang, Ziye Xu, Ziye Xu, Yiling Yang, Yiling Yang, Shanshan Cao, Shanshan Cao, Sali Lyu, Sali Lyu, Weiwei Duan, Weiwei Duan, Weiwei Duan   +12 more
doaj   +1 more source

Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study. [PDF]

PLoS ONE, 2010
Leukocyte telomere length, an emerging marker of biological age, has been shown to predict cardiovascular morbidity and mortality. However, the natural history of telomere length in patients with coronary artery disease has not been studied. We sought to
Ramin Farzaneh-Far, Jue Lin, Elissa Epel, Kyle Lapham, Elizabeth Blackburn, Mary A Whooley   +5 more
doaj   +1 more source

Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population

Communications Biology, 2021
Xuling Chang et al. study whether low frequency variants are associated with leukocyte telomere length and whether these variants predispose to incident cancers and mortalities among East Asians. They find that three East Asian specific variants at POT1,
Xuling Chang, Resham L. Gurung, Ling Wang, Aizhen Jin, Zheng Li, Renwei Wang, Kenneth B. Beckman, Jennifer Adams-Haduch, Wee Yang Meah, Kar Seng Sim, Weng Khong Lim, Sonia Davila, Patrick Tan, Jing Xian Teo, Khung Keong Yeo, Yiamunaa M., Sylvia Liu, Su Chi Lim, Jianjun Liu, Rob M. van Dam, Yechiel Friedlander, Woon-Puay Koh, Jian-Min Yuan, Chiea Chuen Khor, Chew-Kiat Heng, Rajkumar Dorajoo   +25 more
doaj   +1 more source

Association between micronutrients and maternal leukocyte telomere length in early pregnancy in Rwanda

BMC Pregnancy and Childbirth, 2020
Background Exposure to environmental stressors can lead to shorter leukocyte telomere length and increase the risk of chronic diseases. Preservation of leukocyte telomere length by reducing oxidative stress exposure and reinforcing immunity may be a ...
Etienne Nsereko, Aline Uwase, Claude Mambo Muvunyi, Stephen Rulisa, David Ntirushwa, Patricia Moreland, Elizabeth J. Corwin, Nicole Santos, Jue Lin, Jyu-Lin Chen, Manasse Nzayirambaho, Janet M. Wojcicki   +11 more
doaj   +1 more source

Longer leukocyte telomere length is associated with smaller hippocampal volume among non-demented APOE ε3/ε3 subjects. [PDF]

PLoS ONE, 2012
Telomere length shortens with cellular division, and leukocyte telomere length is used as a marker for systemic telomere length. The hippocampus hosts adult neurogenesis and is an important structure for episodic memory, and carriers of the ...
Mikael Wikgren, Thomas Karlsson, Johanna Lind, Therese Nilbrink, Johan Hultdin, Kristel Sleegers, Christine Van Broeckhoven, Göran Roos, Lars-Göran Nilsson, Lars Nyberg, Rolf Adolfsson, Karl-Fredrik Norrback   +11 more
doaj   +1 more source

The relationship between leukocyte mitochondrial DNA copy number and telomere length in community-dwelling elderly women. [PDF]

PLoS ONE, 2013
PURPOSE: Both telomere length and mitochondrial function are accepted as reflective indices of aging. Recent studies have shown that telomere dysfunction may influence impaired mitochondrial biogenesis and function.
Jung-Ha Kim, Hye Kyung Kim, Jae-Hong Ko, Hyoweon Bang, Duk-Chul Lee   +4 more
doaj   +1 more source

Depressive symptoms are not associated with leukocyte telomere length: findings from the Nova Scotia Health Survey (NSHS95), a population-based study. [PDF]

PLoS ONE, 2012
Premature shortening of leukocyte telomere length has been proposed as a novel mechanism by which depression may confer increased risk of adverse cardiovascular events.
Jonathan A Shaffer, Elissa Epel, Min Suk Kang, Siqin Ye, Joseph E Schwartz, Karina W Davidson, Susan Kirkland, Lawrence S Honig, Daichi Shimbo   +8 more
doaj   +1 more source

Monitoring of telomere dynamics in peripheral blood leukocytes in relation to colorectal cancer patients’ outcomes

Frontiers in Oncology, 2022
We investigated the possible associations between leukocyte telomere length, therapy outcomes, and clinicopathological features in patients with colorectal cancer. Additionally, telomerase reverse transcriptase (TERT) expression was evaluated.
Kristyna Tomasova, Kristyna Tomasova, Michal Kroupa, Michal Kroupa, Alzbeta Zinkova, Marie Korabecna, Veronika Vymetalkova, Veronika Vymetalkova, Veronika Vymetalkova, Pavel Skrobanek, Ladislav Sojka, Miroslav Levy, Kari Hemminki, Kari Hemminki, Vaclav Liska, Vaclav Liska, Petr Hosek, Rajiv Kumar, Rajiv Kumar, Ludmila Vodickova, Ludmila Vodickova, Ludmila Vodickova, Pavel Vodicka, Pavel Vodicka, Pavel Vodicka   +24 more
doaj   +1 more source

Shorter leukocyte telomere length is associated with higher risk of infections: a prospective study of 75,309 individuals from the general population

Haematologica, 2017
In the general population, older age is associated with short leukocyte telomere length and with high risk of infections. In a recent study of allogeneic hematopoietic cell transplantation for severe aplastic anemia, long donor leukocyte telomere length ...
Jens Helby, Børge G. Nordestgaard, Thomas Benfield, Stig E. Bojesen   +3 more
doaj   +1 more source

Longer leukocyte telomeres are associated with ultra-endurance exercise independent of cardiovascular risk factors. [PDF]

PLoS ONE, 2013
Telomere length is recognized as a marker of biological age, and shorter mean leukocyte telomere length is associated with increased risk of cardiovascular disease. It is unclear whether repeated exposure to ultra-endurance aerobic exercise is beneficial
Joshua Denham, Christopher P Nelson, Brendan J O'Brien, Scott A Nankervis, Matthew Denniff, Jack T Harvey, Francine Z Marques, Veryan Codd, Ewa Zukowska-Szczechowska, Nilesh J Samani, Maciej Tomaszewski, Fadi J Charchar   +11 more
doaj   +1 more source