Results 11 to 20 of about 8,876 (143)

Outness predicts greater leukocyte telomere length in sexually minoritized men with HIV who use methamphetamine [PDF]

Brain, Behavior, & Immunity - Health
Objective: This longitudinal study aimed to examine the associations of sexual minority stress and outness with leukocyte telomere length across time among sexually minority men (SMM) with HIV who use methamphetamine. Methods: A sample of 91 SMM with HIV
Renessa S. Williams, Ariana Johnson, Michael Miller-Perusse, Annesa Flentje, Judy Moskowitz, Samantha E. Dilworth, Keith J. Horvath, Adam W. Carrico, Brad E. Aouizerat, Delaram Ghanooni   +9 more
doaj   +2 more sources

Contribution of leukocyte telomere length to cardiovascular disease onset from genome-wide cross-trait analysis [PDF]

Nature Communications
Telomere shortening is a well-established marker of cellular aging and genomic instability. While the relationship between leukocyte telomere length and cardiovascular diseases has long been of interest, their genetic interplay remains incompletely ...
Jun Qiao, Qian Wang, Yuhui Zhao, Minjing Chang, Shuo Sun, Pengwei Zhang, Kaixin Yao, Miaoran Chen, Leilei Zheng, Xiaolong Xing, Liuyang Cai, Anil G. Jegga, Lei Jiang, Siim Pauklin, Rongjun Zou, Yining Yang, Yuliang Feng   +16 more
doaj   +2 more sources

Genome wide association and linkage analyses identified three loci -- 4q25, 17q23.2 and 10q11.21 -- associated with variation in leukocyte telomere length: The Long Life Family Study

Frontiers in Genetics, 2014
Leukocyte telomere length is believed to measure cellular aging in humans, and short leukocyte telomere length is associated with increased risks of late onset diseases, including cardiovascular disease, dementia, etc.
Joseph H Lee, Joseph H Lee, Rong eCheng, Lawrence S Honig, Lawrence S Honig, Mary eFeitosa, Candace eKammerer, Min Suk Kang, Nicole eSchupf, Nicole eSchupf, Jiuan eLin, Jason L Sanders, Harold T Bae, Todd eDruley, Thomas T Perls, Kaare eChristensen, Michael eProvince, Richard eMayeux, Richard eMayeux, Richard eMayeux   +19 more
doaj   +1 more source

Leukocyte telomere length in patients with transfusion-dependent thalassemia

BMC Medical Genomics, 2020
Background Thalassemia is a hereditary hemolytic anemia with a severity ranging from mild, non-transfusion dependent to severe chronic anemia requiring lifelong transfusion. Transfusional iron overload is a major complication in patients with transfusion-
Nithita Nanthatanti, Adisak Tantiworawit, Pokpong Piriyakhuntorn, Thanawat Rattanathammethee, Sasinee Hantrakool, Chatree Chai-Adisaksopha, Ekarat Rattarittamrong, Lalita Norasetthada, Wirote Tuntiwechapikul, Kanda Fanhchaksai, Pimlak Charoenkwan, Sirinart Kumfu, Nipon Chattipakorn   +12 more
doaj   +1 more source

Telomere length shortening in hospitalized preterm infants: A pilot study.

PLoS ONE, 2021
Leukocyte telomere length is a biomarker of aging-related health risks. Hospitalized preterm infants frequently experience elevated oxidative stress and inflammation, both of which contribute to telomere shortening.
Mandy Brown Belfort, Farah Qureshi, Jonathan Litt, Michelle Bosquet Enlow, Immaculata De Vivo, Katherine Gregory, Henning Tiemeier   +6 more
doaj   +1 more source

P36 Leukocyte Telomere Length is Inversely Associated with Wave Reflection in 566 Normotensive and Never-treated Hypertensive Subjects

Artery Research, 2020
Background: Telomeres are short segments in chromosome ends, the length of which is reduced during cell life-cycles. We examined the association of leukocyte telomere length and short telomere proportion with hemodynamic variables.
Ilkka Pörsti, Milja Honkonen, Kati Vääräniemi, Outi Saijonmaa, Antti Tikkakoski, Jenni Koskela, Arttu Eräranta, Mika Kähönen, Jukka Mustonen, Frej Fyhrquist   +9 more
doaj   +1 more source

Change in Leukocyte Telomere Length Predicts Mortality in Patients with Stable Coronary Heart Disease from the Heart and Soul Study. [PDF]

PLoS ONE, 2016
Short telomere length independently predicts mortality in patients with coronary heart disease. Whether 5-year change in telomere length predicts subsequent mortality in patients with coronary heart disease has not been evaluated.In a prospective cohort ...
Sarah E Goglin, Ramin Farzaneh-Far, Elissa S Epel, Jue Lin, Elizabeth H Blackburn, Mary A Whooley   +5 more
doaj   +1 more source

Long leukocyte telomere length in prostate cancer patients at diagnosis is associated with poor metastasis-free and cancer-specific survival

Tumor Biology, 2017
Previous studies have suggested that leukocyte telomere length is associated with risk of developing prostate cancer. Investigations of leukocyte telomere length as a prognostic factor in prostate cancer are, however, lacking.
Ulrika Svenson, Göran Roos, Pernilla Wikström   +2 more
doaj   +1 more source

Telomere length and incident atrial fibrillation - data of the PREVEND cohort.

PLoS ONE, 2017
BackgroundThe incidence of atrial fibrillation (AF) increases with age. Telomere length is considered a marker of biological ageing. We investigated the association between leukocyte telomere length and incident AF in the Dutch Prevention of Renal and ...
Joylene E Siland, Bastiaan Geelhoed, Isabelle C van Gelder, Pim van der Harst, Michiel Rienstra   +4 more
doaj   +1 more source

Cognitive Change During the Life Course and Leukocyte Telomere Length in Late Middle-aged Men.

Frontiers in Aging Neuroscience, 2016
Importance: Cognitive skills are known to decline through the lifespan with large individual differences. The molecular mechanisms for this decline are incompletely understood.
Lene Rask, Laila Bendix, Maria Harbo, Birgitte Fagerlund, Erik Lykke Mortensen, Martin Johannes Laurtizen, Merete Osler   +6 more
doaj   +1 more source