Results 201 to 210 of about 594,733 (360)

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

Investigating the Utility of Leukocyte Sialic Acid Measurements in Lysosomal Free Sialic Acid Storage Disorder. [PDF]

JIMD Rep
Sabir MS, Pollard L, Wolfe L, Adams DR, Ciccone C, Leoyklang P, Platt FM, Huizing M, Gahl WA, Malicdan MCV.   +9 more
europepmc   +1 more source

Copper and Iron‐Based Metal‐Organic Frameworks for Synergistic Cancer Phototherapies: Recent Advances, Challenges, and Future Prospects

Advanced Therapeutics, EarlyView.
The graphical abstract illustrates the combined effect of PTT and PDT using metal‐organic frameworks (MOFs) in a cancer treatment model. Tumor‐bearing mice are irradiated with different laser lights, which activate the MOF nanoparticles within cancer cells. The MOFs produce reactive oxygen species through PDT, while PTT elevates the temperature to kill
Kayalvizhi Samuvel Muthiah, Kalaiarasu Lakshminarayanan, Yu Chien Lin, Udesh Dhawan, Loganathan Rangasamy, Ren‐Jei Chung   +5 more
wiley   +1 more source

Laboratory Rat Vaginal Cytology: A Quick Method of Staging Unstained Cells. [PDF]

Cureus
V K S, Raman RK, Kumar S, S B, Farooq J, Noushida N.   +5 more
europepmc   +1 more source

The Experimental Production of Leukocytic Changes in Normal Blood Similar to Le-Cells and Morphologically Identical with Le-Cells1

, 1953
Theo Inderbitzin
openalex   +1 more source

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

Advanced Science, EarlyView.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk, Christa Pfeifhofer‐Obermair, Julia Benz, Natascha Brigo, Milena Bamberger, Alexeja Kleiter, Martin Hermann, Guenter Weiss, Natascha Hermann‐Kleiter   +8 more
wiley   +1 more source

A combined measure of blood leukocytes, forced vital capacity and quantitative CT is highly predictive of mortality in IPF: results of a single-centre cohort study. [PDF]

BMC Pulm Med
Achaiah A, Fraser E, Saunders P, Hoyles R, Benamore R, Ho LP.   +5 more
europepmc   +1 more source

The Efficiency of Oxidative Phosphorylation by Normal and Leukemic Human Leukocytes [PDF]

, 1958
Virginia E. Davis, William L. Wilson, Charles L. Spurr   +2 more
openalex   +1 more source

Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis

Advanced Science, EarlyView.
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao, Ruiyan Ma, Shuai Hao, Xuxin Tan, Xue Zeng, Rui Song, Bing Chen, Zhezhe Cao, Wei Shen, Zhenchun Luo, Jianfeng Huang, He Huang, Liangming Liu, Chenyang Duan   +13 more
wiley   +1 more source

The differential diagnostic potential of SPECT/CT to detect osteomyelitis in foot or ankle: a systematic review. [PDF]

EFORT Open Rev
Sontheimer V, Kemna L, Ruf J, Frodl A, Kühle J, Schmal H.   +5 more
europepmc   +1 more source