Results 31 to 40 of about 21,234 (200)

Progressive multifocal leukoencephalopathy: new concepts

Arquivos de Neuro-Psiquiatria, 2013
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the CNS caused by reactivation of JC virus (JCV) in a setting of cellular immunosuppression.
Marco A. Lima
doaj   +1 more source

Progressive multifocal leukoencephalopathy: rheumatological aspects

Современная ревматология, 2015
Progressive multifocal leukoencephalopathy (PML) is a severe progressive viral disease that affects the central nervous system in patients with immunodeficiency.
Boris Sergeevich Belov
doaj   +1 more source

Progressive multifocal leukoencephalopathy treated with interleukin-7

Clinical Infection in Practice, 2020
Background: Progressive multifocal leukoencephalopathy (PML) is a rare devastating brain infection caused by the JC polyomavirus (JCPyV) in patients with impaired cellular immune responses. In the absence of effective anti-viral therapy, it is unclear if
Karl B. Alstadhaug, Christine Hanssen Rinaldo, Liv Osnes, Irini Sereti, Hilde K. Ofte   +4 more
doaj   +1 more source

Smoldering myeloma presenting as progressive multifocal leukoencephalopathy: a case report

Journal of Medical Case Reports, 2012
Introduction Progressive multifocal leukoencephalopathy is an opportunistic infection occurring in patients with severe cellular immunodeficiency. This case highlights the role of cellular immunodeficiency in the reactivation of John Cunningham virus in ...
Troppmann Martina, Büttner Roland, Böwer Michael, Salzberger Bernd   +3 more
doaj   +1 more source

Brainstem progressive multifocal leukoencephalopathy

European Journal of Neurology, 2020
AbstractBackground and purposeProgressive multifocal leukoencephalopathy (PML) is a severe infection caused by the polyomavirus JC that develops in the central nervous system (CNS) of immunosuppressed patients. The infection frequently starts in the brain hemispheres and can spread into other CNS regions such as the brainstem.
Gautier Breville, Igor J. Koralnik, Patrice H. Lalive   +2 more
openaire   +3 more sources

The Modern Value of Clinical Autopsies

Acta Médica Portuguesa, 2015
Keywords: Autopsy; Antiretroviral Therapy, Highly Active; HIV Infections; Leukoencephalopathy, Progressive Multifocal.
Carlos Marques Pontinha
doaj   +1 more source

Directly Isolated Allogeneic Virus–Specific T Cells in Progressive Multifocal Leukoencephalopathy

JAMA Neurology
This case series investigates if directly isolated allogenic virus–specific T cells are associated with a therapeutic outcome in patients with progressive multifocal leukoencephalopathy (PML).
Nora Möhn, Lea Grote-Levi, M. P. Wattjes, A. Bonifacius, Dennis Holzwart, Franziska Hopfner, Sandra Nay, Sabine Tischer-Zimmermann, M. L. Sassmann, Philipp Schwenkenbecher, K. Sühs, N. Mahmoudi, Clemens Warnke, Julian Zimmermann, D. Hagin, L. Goudeva, Rainer Blasczyk, Armin Koch, B. Maecker-Kolhoff, B. Eiz-Vesper, Günter Höglinger, T. Skripuletz   +21 more
semanticscholar   +1 more source

A Case of Progressive Multifocal Leucoencephalopathy and Cerebral Toxoplasmosis in an HIV-Infected Patient

Acta Medica Bulgarica, 2023
Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection of the central nervous system (CNS) caused by the reactivation of John Cunningham polyomavirus (JCV).
Yancheva-Petrova N., Grozdeva R., Nikolova M., Aleksiev I., Rainova I., Tsvetkova N., Strashimirov D.   +6 more
doaj   +1 more source

JC virus-induced progressive multifocal leukoencephalopathy in a presumably healthy patient

BMC Neurology, 2022
Background JC virus (JCV) is common among healthy individuals and remains latent but may be reactivated under immunosuppressive conditions, resulting in progressive multifocal leukoencephalopathy (PML).
Xiang Wang, Jinxiu Chen, Jing Gong, Ying Wu, Xiang-hao Liu   +4 more
doaj   +1 more source

Myoclonus as an unusual presentation of progressive multifocal leukoencephalopathy in a HIV positive patient [PDF]

Romanian Journal of Neurology, 2012
From mild muscular contractions to gross jerks affecting the whole body, myoclonus is an involuntary movement caused by an excessive discharge from a group of neurons located in one or multiple sites from cortical to peripheral level.
Lucian Chicea, Elena Cecilia Rosca, Ovidiu Rosca, M. Ciolan, Mihaela Simu   +4 more
doaj   +1 more source