IL-17 can be protective or deleterious in murine pneumococcal pneumonia [PDF]
, 2018 Streptococcus pneumoniae is the major bacterial cause of community-acquired pneumonia, and the leading agent of childhood pneumonia deaths worldwide. Nasal colonization is an essential step prior to infection.
Bayes, Hannah K. +4 more
core +3 more sources
Bilateral proliferative retinopathy as the initial presentation of chronic myeloid leukemia. [PDF]
, 2013 The authors report a rare case of a 48-year-old male with chronic myeloid leukemia (CML) who initially presented with a bilateral proliferative retinopathy. The patient complained of recent visual loss and floaters in both eyes (BE).
Barbosa, I. +10 more
core +1 more source
Sequential valproic acid/all-trans retinoic acid treatment reprograms differentiation in refractory and high risk acute myeloid leukemia. [PDF]
, 2006 Epigenetic alterations of chromatin due to aberrant histone deacetylase (HDAC) activity and transcriptional silencing of all-trans retinoic acid (ATRA) pathway are events linked to the pathogenesis of acute myeloid leukemia (AML) that can be targeted by ...
Aloe Spiriti, M +17 more
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Role of Peoxisome Proliferator Activator Receptor đŸ on Blood Retinal Barrier Breakdown
PPAR Research, 2008 The retinal vessels have two barriers: the retinal pigment epithelium and the retinal vascular endothelium. Each barrier exhibits increased permeability under various pathological conditions.
Yasuo Yanagi
doaj +1 more source
Journal of Neuroinflammation, 2019 Background Leukostasis is a key patho-physiological event responsible for capillary occlusion in diabetic retinopathy. Circulating monocytes are the main cell type entrapped in retinal vessels in diabetes.
Mei Chen +6 more
doaj +1 more source
Effects of high versus low flux membranes on O2 saturation in hemodialysis patients [PDF]
, 2013 Background: Several studies have been carried out to evaluate the effects of dialysis on O2 saturation. While the dialysis procedure may lead to hypoxia under different circumstances, there are few studies available on the effects of membrane type on O2 ...
Chandran PK +7 more
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The Scientific World Journal, 2011 We describe a case of severe leukocytosis caused by leukemic mantle cell lymphoma (MCL), complicated by leukostasis with myocardial infarction in which leukapheresis was used in the initial management.
Xuan Duc Nguyen +4 more
doaj +1 more source
Inflammation and endothelial dysfunction are associated with retinopathy: the Hoorn study [PDF]
, 2005 AIMS/HYPOTHESIS: The exact pathogenesis of retinopathy in diabetic and non-diabetic individuals is incompletely understood, but may involve chronic low-grade inflammation and dysfunction of the vascular endothelium.
Bouter, L.M. +7 more
core +4 more sources
The UK Diabetic Retinopathy Electronic Medical Record (UK DR EMR) Users Group, Report 2: real-world data for the impact of cataract surgery on diabetic macular oedema [PDF]
, 2017 Aim: To assess the rate of âtreatment-requiring diabetic macular oedema (DMO)â in eyes for the two âyears before and after cataract surgery. Methods: Multicentre national diabetic retinopathy (DR) database study with anonymised data extraction across ...
Akerele, T. +25 more
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Asian Journal of Transfusion Science, 2017 Introduction: Hyperleukocytosis (HL) and leukostasis seen in myeloid leukemias are a medical emergency. We present a case series of ten such patients in a 4-year period.
Anita A Tendulkar +5 more
doaj +1 more source