Therapeutic Applications of Aggregatibacter actinomycetemcomitans Leukotoxin [PDF]
PathogensAggregatibacter actinomycetemcomitans is a Gram-negative oral bacterium that has been primarily studied for its role in causing periodontal disease. The bacterium has also been implicated in several systemic diseases such as endocarditis and soft tissue ...
Scott C. Kachlany, Brian A. Vega
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Chrysin and Luteolin from Moroccan Propolis to Prevent Aggressive Periodontitis Caused by Aggregatibacter actinomycetemcomitans Leukotoxin: A Computer-Aided Drug Design Approach [PDF]
PharmaceuticalsBackground: Aggregatibacter actinomycetemcomitans is a Gram-negative, facultative anaerobic, immobile oral bacterium responsible for the secretion of virulence factors, namely leukotoxin (LtxA), a large exotoxin of the RTX family that enables the ...
Doha EL Meskini +6 more
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Immunogenicity and protective efficacy of seven candidate vaccines boosted with recombinant proteins, whole-cell bacterins of three serotypes of Mannheimia haemolytica, and an emulsion-type adjuvant [PDF]
Frontiers in Veterinary ScienceIntroductionMannheimia haemolytica is a primary cause of bovine respiratory disease, leading to substantial economic losses in the livestock industry.
Aslı Balevi +4 more
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Biological and molecular characterization of a sheep pathogen isolate of Mannheimia haemolytica and leukotoxin production kinetics [PDF]
Veterinary World, 2021 Background and Aim: Mannheimia haemolytica (Mha) is a common agent of pneumonia in ruminants globally, causing economic losses by morbidity, mortality, and treatment costs.
Dounia Bkiri +10 more
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The Iraqi Journal of Veterinary Medicine, 2012 This study was conducted to extract and titrate the leukotoxin of Fusobacterium necrophorum isolates recovered from 75abscesses found in 24 livers of slaughtered cattle in Sulaimaniyah region.
Suha Ali Hussein
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Leukotoxic activity of Aggregatibacter actinomycetemcomitans and periodontal attachment loss. [PDF]
PLoS ONE, 2014 Aggregatibacter actinomycetemcomitans is a Gram-negative periodontitis-associated bacterium that expresses a toxin that selectively affects leukocytes.
Carola Höglund Åberg +4 more
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Plasma Linoleate Diols Are Potential Biomarkers for Severe COVID-19 Infections
Frontiers in Physiology, 2021 Polyunsaturated fatty acids are metabolized into regulatory lipids important for initiating inflammatory responses in the event of disease or injury and for signaling the resolution of inflammation and return to homeostasis. The epoxides of linoleic acid
Cindy B. McReynolds +13 more
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Toxins, 2018 Bibersteinia trehalosi and Mannheimia haemolytica, originally classified as Pasteurella haemolytica biotype T and biotype A, respectively, under Genus Pasteurella has now been placed under two different Genera, Bibersteinia and Mannheimia, based on DNA ...
Arumugam Murugananthan +4 more
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β-Hemolysis May Not Be a Reliable Indicator of Leukotoxicity of Mannheimia haemolytica Isolates
Toxins, 2018 Mannheimia (Pasteurella) haemolytica causes bronchopneumonia in domestic and wild ruminants. Leukotoxin is the critical virulence factor of M. haemolytica. Since β-hemolysis is caused by a large number of leukotoxin-positive M. haemolytica isolates,
Jegarubee Bavananthasivam +5 more
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Aggregatibacter Actinomycetemcomitans – A Tooth Killer? [PDF]
Journal of Clinical and Diagnostic Research, 2014 Strong evidence is available on Aggregatibacter actinomycetemcomitans (A.a) on its role as the causative agent of localised juvenile periodontitis (LJP), a disease characterised by rapid destruction of the tooth-supporting tissues.
Manoj Raja, Fajar Ummer, C.P Dhivakar
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