Results 41 to 50 of about 5,749 (201)

Lipopolysaccharide Complexes withPasteurella haemolyticaLeukotoxin [PDF]

open access: yesInfection and Immunity, 1999
ABSTRACTThe presence of lipopolysaccharide (LPS) in gram-negative bacterial repeats-in-toxin (RTX) toxin preparations, as well as the harsh conditions required to remove it, suggests that LPS may complex with RTX toxins. Concentrated culture supernatant (CCS) preparations of the RTX toxinPasteurella haemolyticaleukotoxin (LKT) contained LKT and LPS as ...
J, Li, K D, Clinkenbeard
openaire   +2 more sources

Evolution of the leukotoxin promoter in genus Mannheimia

open access: yesBMC Evolutionary Biology, 2009
Background The Mannheimia species encompass a wide variety of bacterial lifestyles, including opportunistic pathogens and commensals of the ruminant respiratory tract, commensals of the ovine rumen, and pathogens of the ruminant integument.
Bisgaard Magne   +7 more
doaj   +1 more source

Nucleotide sequence of the leukotoxin gene from Actinobacillus actinomycetemcomitans: homology to the alpha-hemolysin/leukotoxin gene family [PDF]

open access: yesInfection and Immunity, 1990
The leukotoxin produced by Actinobacillus actinomycetemcomitans has been implicated in the etiology of localized juvenile periodontitis. To initiate a genetic analysis into the role of this protein in disease, we have cloned its gene, lktA. We now present the complete nucleotide sequence of the lktA gene from A. actinomycetemcomitans.
E, Kraig, T, Dailey, D, Kolodrubetz
openaire   +2 more sources

The Microbial Aetiology of Periodontal Diseases [PDF]

open access: yes, 2012
Introduction: The study of the aetiology of periodontal diseases has continued for decades with much progress shown in the last two decades. Having moved through periods of “whole” plaque (with emphasis on mass) being attributed to the disease process,
Africa, Charlene W.J.
core   +2 more sources

Aggregatibacter actinomycetemcomitans Leukotoxin [PDF]

open access: yesJournal of Dental Research, 2010
Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium that colonizes the human oral cavity and is the causative agent for localized aggressive periodontitis (LAP), an aggressive form of periodontal disease that occurs in adolescents. A. actinomycetemcomitans secretes a protein toxin, leukotoxin (LtxA), which helps the bacterium evade the ...
openaire   +2 more sources

Receptor-Based Peptides for Inhibition of Leukotoxin Activity [PDF]

open access: yesACS Infectious Diseases, 2018
The Gram-negative bacterium Aggregatibacter actinomycetemcomitans, commonly associated with localized aggressive periodontitis (LAP), secretes an RTX (repeats-in-toxin) protein leukotoxin (LtxA) that targets human white blood cells, an interaction that is driven by its recognition of the lymphocyte function-associated antigen-1 (LFA-1) integrin.
Eric Krueger   +4 more
openaire   +2 more sources

The Highly Leukotoxic JP2 Genotype of Aggregatibacter actinomycetemcomitans Is Present in the Population of the West African Island, Sal in Cape Verde: A Pilot Study

open access: yesPathogens, 2022
Aggregatibacter actinomycetemcomitans is strongly associated with severe periodontitis, possibly due to its production of a potent leukotoxin. A genetic variant, the JP2 genotype, was found to produce more leukotoxin than the wild type because of a ...
Johannes J. De Soet   +5 more
doaj   +1 more source

Minyak Atsiri Temu Putih (Curcuma Zedoaria Rosc., Zingiberaceae) Menurunkan Ekspresi CD4+ pada Gingiva Terpapar A. Actinomycetemcomitans [PDF]

open access: yes, 2013
Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans)merupakan bakteri Gram-negatif yang dikaitkan dengan penyakit periodontal. Ekspresi positif CD4+ tampak pada keadaan gingivitis(inflamasi gingiva) maupun periodontitis.
Handajani, J. (Juni)
core   +4 more sources

IL-1R and inflammasomes mediate early pulmonary protective mechanisms in respiratory brucella abortus infection [PDF]

open access: yes, 2016
Brucella spp. infection is frequently acquired through contaminated aerosols. The role of interleukin-1 beta (IL-1β) in the early pulmonary response to respiratory Brucella infection is unknown.
Alonso Paiva, Iván Mathias   +9 more
core   +1 more source

Prevalence of JP2 and Non-JP2 Genotypes of Aggregatibacter actinomycetemcomitans and Oral Hygiene Practice of Kenyan Adolescents in Maasai Mara

open access: yesPathogens, 2021
Aggregatibacter actinomycetemcomitans is implicated in the etiology of periodontitis that affects adolescents. The monitoring and mapping of the geographic dissemination pattern of JP2 and non-JP2 genotypes of A. actinomycetemcomitans are of interest. In
Dorte Haubek   +6 more
doaj   +1 more source

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