Results 61 to 70 of about 5,749 (201)

Comparison of virulence genes found in draft genomes of F. necrophorum [PDF]

, 2015
Fusobacterium necrophorum is a causative agent of persistent sore throat syndrome, tonsillar abscesses and Lemierre’s syndrome (LS) in humans. LS is characterised by thrombophlebitis of the jugular vein and bacteraemia.
Greenwell, P., Greenwell, P., Kimmitt, P.T., Kimmitt, P.T., Wright Katie Greenwell Pamela, Wright Katie Greenwell Pamela   +5 more
core  

Phage-mediated horizontal transfer of a Staphylococcus aureus virulence-associated genomic island [PDF]

, 2015
Staphylococcus aureus is a major pathogen of humans and animals. The capacity of S. aureus to adapt to different host species and tissue types is strongly influenced by the acquisition of mobile genetic elements encoding determinants involved in niche ...
C Goerke, C Wirtz, CM Guinane, DA Robinson, DY Thomas, JA Lindsay, JA Lindsay, JA Lindsay, JR Fitzgerald, L Herron-Olson, L Tao, M Arnaud, M Deghorain, M Feiss, M Kuroda, MD Sam, N Quiles-Puchalt, RG Everitt, RP Novick, S Holtfreter, T Baba, T Baba, T Ohta   +22 more
core   +3 more sources

Secretion of RTX Leukotoxin by Actinobacillus actinomycetemcomitans [PDF]

Infection and Immunity, 2000
ABSTRACT Actinobacillus actinomycetemcomitans , the etiologic agent for localized juvenile periodontitis and certain other human infections, such as endocarditis, expresses a leukotoxin that acts on polymorphonuclear leukocytes and macrophages.
S C, Kachlany, D H, Fine, D H, Figurski
openaire   +2 more sources

Aggregatibacter actinomycetemcomitans Leukotoxin Is Delivered to Host Cells in an LFA-1-Indepdendent Manner When Associated with Outer Membrane Vesicles

Toxins, 2018
The Gram-negative bacterium, Aggregatibacter actinomycetemcomitans, has been associated with localized aggressive periodontitis (LAP). In particular, highly leukotoxic strains of A.
Justin B. Nice, Nataliya V. Balashova, Scott C. Kachlany, Evan Koufos, Eric Krueger, Edward T. Lally, Angela C. Brown   +6 more
doaj   +1 more source

Complete Genome Sequence of the Disinfectant Susceptibility Testing Reference Strain Staphylococcus aureus subsp. aureus ATCC 6538 [PDF]

, 2017
We report here the complete genome sequence of the methicillin-sensitive Staphylococcus aureus subsp. aureus strain ATCC 6538 (FDA 209, DSM 799, WDCM 00032, and NCTC 10788)
Johnston, Paul, Makarova, Olga, Roesler, Uwe, Rolff, Jens, Walther, Birgit   +4 more
core   +1 more source

Differential Cell Lysis Among Periodontal Strains of JP2 and Non-JP2 Genotype of Aggregatibacter actinomycetemcomitans Serotype B Is Not Reflected in Dissimilar Expression and Production of Leukotoxin

Pathogens, 2019
Leukotoxic potential of Aggregatibacter actinomycetemcomitans strains has been studied by the use of several methods, and results differ depending on the methods used.
Anne Birkeholm Jensen, Marianne Lund, Niels Nørskov-Lauritsen, Anders Johansson, Rolf Claesson, Jesper Reinholdt, Dorte Haubek   +6 more
doaj   +1 more source

Aggregatibacter actinomycetemcomitans Leukotoxin Activates the NLRP3 Inflammasome and Cell-to-Cell Communication

Pathogens, 2022
Carriers of highly leukotoxic genotypes of Aggregatibacter actinomycetemcomitans are at high risk for rapid degradation of tooth-supporting tissues. The leukotoxin (LtxA) expressed by this bacterium induces a rapid pro-inflammatory response in leukocytes
Peyman Kelk, Nick Sina Moghbel, Josefine Hirschfeld, Anders Johansson   +3 more
doaj   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source

Leukotoxin and pyrogenic toxin Superantigen gene backgrounds in bloodstream and wound Staphylococcus aureus isolates from eastern region of China

BMC Infectious Diseases, 2018
Background The bicomponent leukotoxins and the pyrogenic toxin superantigens (PTSAgs) are important virulence factors of Staphylococcus aureus. It is necessary to survey the prevalence and expression of these toxin-encoding genes for understanding the ...
Chunyan He, Su Xu, Huanqiang Zhao, Fupin Hu, Xiaogang Xu, Shu Jin, Han Yang, Fang Gong, Qingzhong Liu   +8 more
doaj   +1 more source

Biofilm formation among methicillin-resistant Staphylococcus aureus isolates from patients with urinary tract infection. [PDF]

, 2004
Staphylococci have been confirmed to form biofilms on various biomaterials. The purpose of this study was to investigate biofilm formation among methicillin-resistant Staphylococcus aureus (MRSA) isolates from patients with urinary tract infection (UTI ...
Ando, Eiichi, Kariyama, Reiko, Kumon, Hiromi, Mitsuhata, Ritsuko, Monden, Koichi   +4 more
core   +1 more source