Results 71 to 80 of about 5,749 (201)
ABSTRACT This case report describes a novel presentation of Aggregatibacter actinomycetemcomitans causing deep neck abscess, mediastinitis, and deep vein thrombosis. Clinicians should be aware that this organism can cause invasive extra‐oral infection.
Joshua Sia, Carly Hughes
wiley +1 more source
Aggregatibacter actinomycetemcomitans is a periodontal pathogen colonizing the oral cavity in many individuals of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade the host ...
Jan Oscarsson +2 more
doaj +1 more source
Mucosa-Environment Interactions in the Pathogenesis of Rheumatoid Arthritis [PDF]
Mucosal surfaces play a central role in the pathogenesis of rheumatoid arthritis (RA). Several risk factors, such as cigarette smoking, environmental pollution, and periodontitis interact with the host at the mucosal level, triggering immune system ...
Conti, Fabrizio +5 more
core +1 more source
Immunology of the Outer Membrane Proteins of Pasteurella Haemolytica A2, A7 and A9 in Sheep [PDF]
Pneumonic pasteurellosis is a common respiratory disease of goats and sheep throughout the world, including Malaysia. In Malaysia, Pasteurella haemolytica A2 is most commonly isolated from cases of pneumonic pasteurellosis in sheep and goats followed by ...
Mohd Yusoff, Md Sabri
core
Effects of Aggregatibacter actinomycetemcomitans leukotoxin on endothelial cells
Aggregatibacter actinomycetemcomitans is a human pathogen that produces leukotoxin (LtxA) as a major virulence factor. In this study the effect of LtxA on microvascular endothelial cell viability and phenotype was studied. High doses of single LtxA treatment (500 ng/ml to 5 μg/ml) significantly and irreversibly decreased cell proliferation and induced ...
Dietmann, Anelia +5 more
openaire +2 more sources
Staphylococcus aureus is a leading cause of foodborne diarrhea, primarily due to staphylococcal enterotoxins (SEs). This study employed whole‐genome sequencing to characterize 106 S. aureus isolates from diarrheal patients in East China (2019–2024). We identified 23 sequence types, with ST398 (22.6%) and ST5 (7.5%) among the most prevalent.
Jinzhi Zhang +7 more
wiley +1 more source
The Escherichia coli hemolysin (HlyA) is a pore-forming exotoxin associated with severe complications of human urinary tract infections. HlyA is the prototype of the repeats-in-toxin (RTX) family, which includes LtxA from Aggregatibacter ...
Laura C. Ristow +6 more
doaj +1 more source
Lipopolysaccharides mediate leukotoxin secretion in Aggregatibacter actinomycetemcomitans [PDF]
SummaryWe previously reported that lipopolysaccharide (LPS) ‐related sugars are associated with the glycosylation of the collagen adhesin EmaA, a virulence determinant of Aggregatibacter actinomycetemcomitans. In this study, the role of LPS in the secretion of other virulence factors was investigated.
G, Tang +3 more
openaire +2 more sources
Salivary multiomics from healthy, PD, RA, and PD‐RA cohorts identified PD−/RA‐linked microbial and metabolic signatures. We then transplanted salivary microbiota from a PD donor or a healthy donor into collagen‐induced arthritis mice. PD microbiota colonized the gut, reshaped communities, weakened epithelial tight junctions, and provoked systemic ...
Ruiyang Ge +9 more
wiley +1 more source
Microbial Community Composition Impacts Pathogen Iron Availability during Polymicrobial Infection [PDF]
Iron is an essential nutrient for bacterial pathogenesis, but in the host, iron is tightly sequestered, limiting its availability for bacterial growth. Although this is an important arm of host immunity, most studies examine how bacteria respond to iron ...
Abraham, Nader +3 more
core +4 more sources

