Results 171 to 180 of about 84,306 (206)
Effect of Aspirin Challenge on Innate Lymphoid Cells in Asthma Patients With Aspirin Hypersensitivity. [PDF]
Eur J ImmunolKacorzyk R +6 more
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Annual Review of Biochemistry, 1983
The leukotrienes are a family of biologically active molecules, formed by leukocytes, mastocytoma cells, macrophages, and other tissues and cells in response to immunological and nonimmunological stimuli. They exhibit a number of biological effects such as contraction of bronchial smooth muscles, stimulation of vascular permeability, and attraction and
Richard H. Green, Paul F. Lambeth
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The leukotrienes are a family of biologically active molecules, formed by leukocytes, mastocytoma cells, macrophages, and other tissues and cells in response to immunological and nonimmunological stimuli. They exhibit a number of biological effects such as contraction of bronchial smooth muscles, stimulation of vascular permeability, and attraction and
Richard H. Green, Paul F. Lambeth
+5 more sources
Medical Clinics of North America, 2002
Leukotrienes (LTs) are 5-lipoxygenase products formed from arachidonic acid metabolism. There is compelling evidence that LTs play an important role in the pathogenesis of asthma. LTs affect vascular permeability, mucus production, and smooth muscle constriction, and may contribute to airway remodeling.
Teal S, Hallstrand, William R, Henderson
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Leukotrienes (LTs) are 5-lipoxygenase products formed from arachidonic acid metabolism. There is compelling evidence that LTs play an important role in the pathogenesis of asthma. LTs affect vascular permeability, mucus production, and smooth muscle constriction, and may contribute to airway remodeling.
Teal S, Hallstrand, William R, Henderson
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Allergy and Asthma Proceedings, 1991
Bronchial asthma is characterized by airways' inflammation and airways' hyperresponsiveness. It is unlikely that the pathophysiology of asthma and bronchial hyperresponsiveness can be explained on the basis of a single cell or a single class of mediators.
T H, Lee, J, Arm
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Bronchial asthma is characterized by airways' inflammation and airways' hyperresponsiveness. It is unlikely that the pathophysiology of asthma and bronchial hyperresponsiveness can be explained on the basis of a single cell or a single class of mediators.
T H, Lee, J, Arm
openaire +2 more sources
Clinics in Liver Disease, 2003
Hepatotoxicity is the most common cause of fulminant hepatic failure in the United States and the main indication for market withdrawal of drugs. This condition has been increasingly recognized as a problem of enormous medical, financial legal, and regulatory importance.
Timothy J, Davern, Nathan M, Bass
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Hepatotoxicity is the most common cause of fulminant hepatic failure in the United States and the main indication for market withdrawal of drugs. This condition has been increasingly recognized as a problem of enormous medical, financial legal, and regulatory importance.
Timothy J, Davern, Nathan M, Bass
openaire +2 more sources
The International Journal of Biochemistry & Cell Biology, 1998
Leukotriene B4 is a pro-inflammatory mediator synthesised in myeloid cells from arachidonic acid. Synthesis is catalysed by 5-lipoxygenase and leukotriene A4 hydrolase and is increased by inflammatory mediators including endotoxin, complement fragments, tumor necrosis factor and interleukins.
S W, Crooks, R A, Stockley
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Leukotriene B4 is a pro-inflammatory mediator synthesised in myeloid cells from arachidonic acid. Synthesis is catalysed by 5-lipoxygenase and leukotriene A4 hydrolase and is increased by inflammatory mediators including endotoxin, complement fragments, tumor necrosis factor and interleukins.
S W, Crooks, R A, Stockley
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Journal of Receptor Research, 1989
Leukotrienes are metabolites of arachidonic acid catalyzed by a novel lipoxygenase specific for the C-5 position. These fatty acids have many pharmacological properties including smooth muscle contractions and leukocytes activation, and are believed to play a key role in inflammatory and hypersensitivity reactions.
J P, Cristol, B, Provençal, P, Sirois
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Leukotrienes are metabolites of arachidonic acid catalyzed by a novel lipoxygenase specific for the C-5 position. These fatty acids have many pharmacological properties including smooth muscle contractions and leukocytes activation, and are believed to play a key role in inflammatory and hypersensitivity reactions.
J P, Cristol, B, Provençal, P, Sirois
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Leukotrienes and Atherosclerosis
Current Drug Targets, 2010Evidence from experimental and genetic studies suggest the existence of a potential link between the leukotrienes (LT) signalling cascade, and the pathogenesis/progression of atherosclerosis and its serious consequences such as acute myocardial infarction (AMI), stroke, aortic aneurysms, and intimal hyperplasia.
G. Riccioni, M. Bäck, V. Capra
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