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Leukotriene A4: Enzymatic conversion to leukotriene C4
Biochemical and Biophysical Research Communications, 1980Abstract An unstable epoxide, leukotriene A4 (5(S)- trans -5,6-oxido-7,9- trans -11,14- cis -eicosatetraenoic acid), was earlier proposed to be an intermediate in the conversion of arachidonic acid into the slow reacting substance (SRS), leukotriene C4.
O, Rådmark, C, Malmsten, B, Samuelsson
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Journal of Lipid Mediators and Cell Signalling, 1995
The current challenge in research on leukotriene receptors is to clone these molecules. Traditional protein purification approaches have not been successful in providing sequence information. Solubilization of cys-LT1 has been achieved but results in the dissociation of G-proteins and the loss of high affinity binding (Mong et al., 1986b; Mong and ...
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The current challenge in research on leukotriene receptors is to clone these molecules. Traditional protein purification approaches have not been successful in providing sequence information. Solubilization of cys-LT1 has been achieved but results in the dissociation of G-proteins and the loss of high affinity binding (Mong et al., 1986b; Mong and ...
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La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1984
Leukotrienes are released in inflammatory and immediate hypersensitivity reactions. Leukotrienes are novel metabolites of arachidonic acid produced by the lungs and leucocytes. Their formation is catalyzed by a specific 5-lipoxygenase. The key compound of this pathway is leukotriene A4 which is transformed either into leukotriene B4 by enzymatic ...
P, Sirois, P, Borgeat
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Leukotrienes are released in inflammatory and immediate hypersensitivity reactions. Leukotrienes are novel metabolites of arachidonic acid produced by the lungs and leucocytes. Their formation is catalyzed by a specific 5-lipoxygenase. The key compound of this pathway is leukotriene A4 which is transformed either into leukotriene B4 by enzymatic ...
P, Sirois, P, Borgeat
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Leukotriene A4 hydrolase and leukotriene B4 metabolism
Journal of Lipid Mediators and Cell Signalling, 1995T, Yokomizo +5 more
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