Results 211 to 220 of about 98,896 (358)

Persistent Eosinophilic Inflammation in Adult Asthmatics with High Serum and Urine Levels of Leukotriene E4

, 2021
Ga‐Young Ban, Seung‐Hyun Kim, Hae‐Sim Park   +2 more
openalex   +2 more sources

Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade, Rhiannon Potter, Alex Inskip, Jane Nesworthy, Kirsti Brock, Gill Norman   +5 more
wiley   +1 more source

GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling

British Journal of Pharmacology, Volume 183, Issue 11, Page 2619-2633, June 2026.
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley   +1 more source

Multi-Omics Analysis Identified <i>LTB4R</i> as a Peripheral Blood Diagnostic Biomarker for Colorectal Cancer. [PDF]

Int J Mol Sci
Wang T, Li C, Wang Z.
europepmc   +1 more source

Depletion of glutathione selectively inhibits synthesis of leukotriene C by macrophages.

, 1981
Carol A. Rouzer, William Scott, Owen W. Griffith, A L Hamill, Zanvil A. Cohn   +4 more
openalex   +2 more sources

Directed Vascular Expression of Human Cysteinyl Leukotriene 2 Receptor Modulates Endothelial Permeability and Systemic Blood Pressure [PDF]

, 2004
Yiqun Hui, Yan Cheng, Isabella Smalera, Wenying Jian, Lawrence Goldhahn, Garret A. FitzGerald, Colin Funk   +6 more
openalex   +1 more source

Distinct Roles of Myeloid‐ and Hepatocyte‐PLA2G6 Deletion in Mice With Metabolic Dysfunction‐Associated Steatotic Liver Disease

Liver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Polymorphisms of group VIA calcium‐independent phospholipase A2 (iPLA2β or PLA2G6) are associated with Type‐2 diabetes, blood lipids and inflammation. Global deficiency in iPLA2β‐null mice elicited protection against hepatic steatosis but not hepatic inflammation after high‐fat diet (HFD) feeding.
Gang Li, Simone Staffer, Sabine Tuma‐Kellner, Uta Merle, Walee Chamulitrat   +4 more
wiley   +1 more source

Total oxylipin concentrations in NIST SRM 1950 plasma compared to fresh and commercially obtained human plasma. [PDF]

J Lipid Res
Kampschulte N, Scholz L, Pedersen TL, Snodgrass IF, Newman JW, Schebb NH.   +5 more
europepmc   +1 more source

Inhaled glucocorticoids versus leukotriene receptor antagonists as single agent asthma treatment: systematic review of current evidence [PDF]

, 2003
FM Ducharme
openalex   +1 more source

Heterogeneous Causes of Acute Respiratory Distress Syndrome Correlate With Distinct Peripheral Polyunsaturated Fatty Acid Metabolites

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Inflammatory insults, such as sepsis, pneumonia, aspiration, or trauma can trigger an inflammatory reaction leading to Acute Respiratory Distress Syndrome (ARDS). This study identified that different causes lead to differences in n−3 and n−6 polyunsaturated fatty acids (PUFAs) and their downstream oxylipins.
Laura A. Leuenberger, Joseph S. Bednash, Evangeline Schott, Carmen Mikacenic, Eric D. Morrell, Carson Richardson, Lynn A. Fussner, Jeffrey C. Horowitz, Rama K. Mallampalli, Saame Raza Shaikh, Robert M. Tighe, Kymberly M. Gowdy   +11 more
wiley   +1 more source