Results 291 to 300 of about 98,896 (358)
Molecular insights into ago-allosteric modulation at cysteinyl leukotriene receptor 2. [PDF]
Nat CommunLi M +12 more
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Gut microbiota metabolites and key target molecules in allergic rhinitis: a multi-omics study of gut-nose axis regulation via the inflammation-metabolism network. [PDF]
Front MicrobiolZhang J +9 more
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Dietary Antigen Interaction with Intestinal Epithelial Cells. [PDF]
Curr Allergy Asthma RepReichel PE +3 more
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International Journal of Biochemistry and Cell Biology, 1998
Leukotriene B4 is a pro-inflammatory mediator synthesised in myeloid cells from arachidonic acid. Synthesis is catalysed by 5-lipoxygenase and leukotriene A4 hydrolase and is increased by inflammatory mediators including endotoxin, complement fragments, tumor necrosis factor and interleukins.
S W, Crooks, R A, Stockley
exaly +3 more sources
Leukotriene B4 is a pro-inflammatory mediator synthesised in myeloid cells from arachidonic acid. Synthesis is catalysed by 5-lipoxygenase and leukotriene A4 hydrolase and is increased by inflammatory mediators including endotoxin, complement fragments, tumor necrosis factor and interleukins.
S W, Crooks, R A, Stockley
exaly +3 more sources
Annual Review of Biochemistry, 1983
The leukotrienes are a family of biologically active molecules, formed by leukocytes, mastocytoma cells, macrophages, and other tissues and cells in response to immunological and nonimmunological stimuli. They exhibit a number of biological effects such as contraction of bronchial smooth muscles, stimulation of vascular permeability, and attraction and
Richard H. Green, Paul F. Lambeth
openaire +3 more sources
The leukotrienes are a family of biologically active molecules, formed by leukocytes, mastocytoma cells, macrophages, and other tissues and cells in response to immunological and nonimmunological stimuli. They exhibit a number of biological effects such as contraction of bronchial smooth muscles, stimulation of vascular permeability, and attraction and
Richard H. Green, Paul F. Lambeth
openaire +3 more sources
Allergy and Asthma Proceedings, 1991
Bronchial asthma is characterized by airways' inflammation and airways' hyperresponsiveness. It is unlikely that the pathophysiology of asthma and bronchial hyperresponsiveness can be explained on the basis of a single cell or a single class of mediators.
T H, Lee, J, Arm
openaire +2 more sources
Bronchial asthma is characterized by airways' inflammation and airways' hyperresponsiveness. It is unlikely that the pathophysiology of asthma and bronchial hyperresponsiveness can be explained on the basis of a single cell or a single class of mediators.
T H, Lee, J, Arm
openaire +2 more sources
Leukotrienes and Atherosclerosis
Current Drug Targets, 2010Evidence from experimental and genetic studies suggest the existence of a potential link between the leukotrienes (LT) signalling cascade, and the pathogenesis/progression of atherosclerosis and its serious consequences such as acute myocardial infarction (AMI), stroke, aortic aneurysms, and intimal hyperplasia.
G. Riccioni, M. Bäck, V. Capra
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PEDIATRICS, 2002
Leukotrienes (LTs) are 5-lipoxygenase products formed from arachidonic acid metabolism. There is compelling evidence that LTs play an important role in the pathogenesis of asthma. LTs affect vascular permeability, mucus production, and smooth muscle constriction, and may contribute to airway remodeling.
H William, Kelly, Hans, Bisgaard
openaire +4 more sources
Leukotrienes (LTs) are 5-lipoxygenase products formed from arachidonic acid metabolism. There is compelling evidence that LTs play an important role in the pathogenesis of asthma. LTs affect vascular permeability, mucus production, and smooth muscle constriction, and may contribute to airway remodeling.
H William, Kelly, Hans, Bisgaard
openaire +4 more sources
Pharmacology & Therapeutics, 1990
The leukotrienes are synthesized from essential fatty acids via a 5-lipoxygenase enzyme. Most is known about the four-series leukotrienes derived from arachidonic acid. Leukotriene B4 is a potent chemotactic agent for leukocytes and it induces neutrophil-dependent increased microvascular permeability. Leukotrienes C4, D4 and E4 are bronchoconstrictors;
S D, Brain, T J, Williams
openaire +2 more sources
The leukotrienes are synthesized from essential fatty acids via a 5-lipoxygenase enzyme. Most is known about the four-series leukotrienes derived from arachidonic acid. Leukotriene B4 is a potent chemotactic agent for leukocytes and it induces neutrophil-dependent increased microvascular permeability. Leukotrienes C4, D4 and E4 are bronchoconstrictors;
S D, Brain, T J, Williams
openaire +2 more sources