Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 4, April 2026.This study investigated whether Lacticaseibacillus paracasei Zhang could alleviate the gut microbiota imbalance and its systemic consequences caused by antibiotics. Mice treated with azithromycin exhibited gut microbiota disorders, and subsequent probiotic intervention was carried out.
Xiaoye Liu +4 more
wiley +1 more source
The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein [PDF]
, 2006 Affiliation: Unité de recherche en Arthrose, Centre de recherche du Centre Hospitalier de l'Université de Montréal, Hôpital Notre-DameOsteoarthritis (OA) is characterized by articular cartilage degradation and hypertrophic bone changes with osteophyte ...
Kelitha Maxis +6 more
core +2 more sources
Journal of Pharmacological Sciences, 2011 Formyl peptide receptor 1 (FPR1) and FPR2/ALX are known to control neutrophil chemotaxis in response to various ligands. In this study, we investigated the inhibitory mechanism of compound 43 (Cpd43), an FPR1 and FPR2/ALX dual agonist, on human ...
Yoshitaka Sogawa +3 more
doaj +1 more source
Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]
, 1999 The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT +28 more
core +1 more source
SARS-CoV Regulates Immune Function-Related Gene Expressions in Human Monocytic Cells [PDF]
, 2011 Background: Severe Acute Respiratory Syndrome (SARS) is characterized by acute respiratory distress (ARDS) and pulmonary fibrosis, and the monocyte/macrophage is the key player in the pathogenesis of SARS. Methods: In this study, we ...
Betty A. Wu-Hsieh +4 more
core +1 more source
Ccl2 and Ccl3 Mediate Neutrophil Recruitment via Induction of Protein Synthesis and Generation of Lipid Mediators [PDF]
, 2009 Objective: Although the chemokines monocyte chemoattractant protein-1 (Ccl2/JE/MCP-1) and macrophage inflammatory protein-1α (Ccl3/MIP-1α) have recently been implicated in neutrophil migration, the underlying mechanisms remain largely unclear.
Berberich, Nina +7 more
core +1 more source
Antimicrobial peptides and eicosanoids : roles and interactions in inflammation and host defense [PDF]
, 2017 Antimicrobial peptides (AMPs) have a broad spectrum of activities and exert their functions by both direct killing of microbes through the interaction with the microbial membrane, and modulation of innate and adaptive immunity of the host.
Tang, Xiao
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Journal of Pharmacological Sciences, 2007 We investigated whether leukotriene B4 (LTB4) and its signaling pathway play an important role in the progression of human colon cancer via a direct stimulation of cancer cell proliferation.
Aya Ihara +5 more
doaj +1 more source
Leukotriene B4 enhances the generation of proinflammatory microRNAs to promote MyD88-dependent macrophage activation [PDF]
, 2014 MicroRNAs are known to control TLR activation in phagocytes. We have shown that leukotriene (LT) B4 (LTB4) positively regulates macrophage MyD88 expression by decreasing suppressor of cytokine signaling-1 (SOCS-1) mRNA stability.
Filgueiras, Luciano +6 more
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