Results 71 to 80 of about 29,391 (230)
Apremilast in Japanese patients with palmoplantar pustulosis: A randomized, Phase 3 trial
Journal of the European Academy of Dermatology and Venereology, EarlyView.In this Phase 3 trial of Japanese patients with moderate to severe PPP (NCT05174065), significantly more patients achieved PPPASI‐50 at Week 16 with apremilast versus placebo. Patient‐reported outcomes, including pruritus and pain/discomfort, also showed significantly greater decreases at Week 16 with apremilast versus placebo.
Tadashi Terui +15 more
wiley +1 more source
Праці Наукового товариства імені Шевченка. Медичні науки, 2019 LEUKOTRIENE B4 AND PROSTAGLANDIN E2 LEVELS IN PATIENTS WITH NSAID-GASTROPATHY AFTER PANTOPRAZOLE ...
K. Kvit +3 more
doaj
Journal of Periodontal Research, EarlyView.This review describes the features of grade C molar‐incisor pattern periodontitis and discusses the role of A. actinomycetemcomitans in its pathogenesis and why molars and incisors are preferably affected. Possible future studies on this aggressive disease in primary and permanent dentition and emerging omics techniques for diagnosis and management are
Luigi Nibali +3 more
wiley +1 more source
PPAR Research, 2008 Pancreatic cancer is a devastating disease in which current therapies are inadequate. Separate lines of research have identified the 5-lipoxygenase/leukotriene B4 receptor pathway and the PPAR𝛾 pathway as potential targets for prevention or treatment of ...
Thomas E. Adrian +3 more
doaj +1 more source
Frontiers in Pharmacology, 2020 The pathogenesis of preeclampsia (PE) involves several pathophysiological processes that may be affected by glucocorticoid (GC). We confirmed previously that GC exposure could result in PE, while PE is linked to a deficiency of lipoxin A4 (LXA4), an ...
Haojing Liu +5 more
doaj +1 more source
Leukotriene B4, administered via intracerebroventricular injection, attenuates the antigen-induced asthmatic response in sensitized guinea pigs [PDF]
, 2010 Background Despite intensive studies focused on the pathophysiology of asthmatic inflammation, little is known about how cross-talk between neuroendocrine and immune systems regulates the inflammatory response during an asthmatic attack.
Yi-Liang Zhu +5 more
core +2 more sources
Leukotriene B4 as a marker of cerebral dysfunction [PDF]
Anaesthesia, 1995 Summary It has been postulated that leukotriene B4 is involved in the pathogenesis of postisehaemie cerebral oedema. We set out to determine if a relationship exists between jugular bulb leukotriene B4 and other indicators of cerebral ischaemia.
A P, Kendall, E S, Lin, T E, Oh
openaire +2 more sources
Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence
Journal of Periodontal Research, EarlyView.This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo +3 more
wiley +1 more source
Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity Reviews, EarlyView.Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
Inhibition of release of inflammatory in primary and cultured cells by a Chinese herbal medicine formula for allergic rhinitis [PDF]
, 2007 BACKGROUND - We demonstrated that a Chinese herbal formula, which we refer to as RCM-101, developed from a traditional Chinese medicine formula, reduced nasal and non-nasal symptoms of seasonal allergic rhinitis (SAR).
Lenon, G +5 more
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