Results 71 to 80 of about 15,891 (187)

Biosynthesis of eicosanoids and transcellular metabolism of leukotrienes in murine bone marrow cells

Journal of Lipid Research, 2007
Leukotriene B4 (LTB4) biosynthesis by polymorphonuclear leukocytes (PMNs) is an important factor of inflammatory responses. PMNs also release LTA4, an unstable intermediate that can be taken up by neighboring cells and metabolized into LTC4. Most studies
Miguel A. Gijón, Simona Zarini, Robert C. Murphy   +2 more
doaj   +1 more source

Epicardial adipose tissue‐linked leukotriene and cytokine signalling pathways – novel targets for prevention of obesity‐ and diabetes‐linked ventricular arrhythmia

The Journal of Physiology, EarlyView.
Kelly A. Aromolaran, Ademuyiwa S. Aromolaran   +1 more
wiley   +1 more source

Role of human RNase 7 in neuronal and glial cell models: moving towards an unexpected new functional link

The FEBS Journal, Volume 293, Issue 15, Page 4660-4679, August 2026.
Human RNase 7 is known to exert antimicrobial activity in epithelial tissues. Here, using SH‐SY5Y and U‐87 MG, neuroblastoma and glioblastoma cell lines, respectively, we found that RNase 7 enhances immune responses to LPS stimulation by reducing the expression of pro‐inflammatory cytokines, nitric oxide, and ROS.
Rosanna Culurciello, Maria Cristiano, Ilaria Di Nardo, Ida Palumbo, Erika Piccolo, Rosario Oliva, Andrea Bosso, Aldo Donizetti, Eugenio Notomista, Elio Pizzo   +9 more
wiley   +1 more source

Signal transduction and activation of the NADPH oxidase in eosinophils

Memorias do Instituto Oswaldo Cruz, 1997
Activation of the eosinophil NADPH oxidase and the subsequent release of toxic oxygen radicals has been implicated in the mechanism of parasite killing and inflammation.
Mark A Lindsay, Mark A Giembycz
doaj   +1 more source

The effectiveness of unfractionated heparin vs. low molecular weight (Enoxaparin) in Acute Respiratory Distress Syndrom (ARDS) and metabolic dysfunction: an old drug for new indication!

BMC Immunology
Background Acute Respiratory Distress Syndrome is a lung disorder defined by the acute onset of hypoxemia, the commonest being abdominal sepsis.Many biomarkers have been studied for diagnostic prognostication and ARDS pharmacotherapy.
Shabnam Delasoud, Mojtaba Mojtahedzadeh, Mohammad Sharifzadeh, Mohammad Hossein Ghahremani, Abbass Kebriaeezadeh, Maryam Gholami, Samin Sabzevari, Omid Sabzevari   +7 more
doaj   +1 more source

A genetically encoded sensor for visualizing leukotriene B4 gradients in vivo. [PDF]

Nat Commun, 2023
Tamás SX, Roux BT, Vámosi B, Dehne FG, Török A, Fazekas L, Enyedi B.   +6 more
europepmc   +1 more source

Leukotriene B4 receptor 1 (BLT1) does not mediate disease progression in a mouse model of liver fibrosis. [PDF]

Biochem J, 2023
Coyne E, Nie Y, Abdurrachim D, Ong CLZ, Zhou Y, Ali AAB, Meyers S, Grein J, Blumenschein W, Gongol B, Liu Y, Hugelshofer CL, Carballo-Jane E, Talukdar S.   +13 more
europepmc   +1 more source

NLRP3 is essential for neutrophil polarization and chemotaxis in response to leukotriene B4 gradient. [PDF]

Proc Natl Acad Sci U S A, 2023
Van Bruggen S, Jarrot PA, Thomas E, Sheehy CE, Silva CMS, Hsu AY, Cunin P, Nigrovic PA, Gomes ER, Luo HR, Waterman CM, Wagner DD.   +11 more
europepmc   +1 more source

Leukotriene B4 Loaded in Microspheres Inhibits Osteoclast Differentiation and Activation. [PDF]

Braz Dent J, 2022
Lorencetti-Silva F, Arnez MFM, Thomé JPQ, Carvalho MS, Carvalho FK, Queiroz AM, Faccioli LH, Paula-Silva FWG.   +7 more
europepmc   +1 more source

A disease-associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer. [PDF]

J Cachexia Sarcopenia Muscle, 2022
Smeets E, Huang S, Lee XY, Van Nieuwenhove E, Helsen C, Handle F, Moris L, El Kharraz S, Eerlings R, Devlies W, Willemsen M, Bücken L, Prezzemolo T, Humblet-Baron S, Voet A, Rochtus A, Van Schepdael A, de Zegher F, Claessens F.   +18 more
europepmc   +1 more source