Results 61 to 70 of about 18,529 (226)
Mediators of Inflammation, 2004 AIM: To determine induced sputum cell counts and interleukin-8 (IL-8), tumor necrosis factor alpha (TNF-α) and leukotriene B4 (LTB4) levels as markers of neutrophilic inflammation in moderate persistent asthma, and to evaluate the response to inhaled ...
Ilknur Basyigit +4 more
doaj +1 more source
The FEBS Journal, EarlyView.Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah +5 more
wiley +1 more source
Esculetin reduces leukotriene B4 level in plasma of rats with adjuvant-induced arthritis
, 2016 Objectives : Esculetin (6,7-dihydroxycoumarin) is a natural coumarin with anti-oxidant, anti-inflammatory and anti-nociceptive activity. It acts as a potent inhibitor of lipoxygenases (5-LOX and 12-LOX) and decreases the production of matrix ...
Przemysław Rzodkiewicz +5 more
core +1 more source
PPAR Research, 2008 Pancreatic cancer is a devastating disease in which current therapies are inadequate. Separate lines of research have identified the 5-lipoxygenase/leukotriene B4 receptor pathway and the PPAR𝛾 pathway as potential targets for prevention or treatment of ...
Thomas E. Adrian +3 more
doaj +1 more source
Frontiers in Pharmacology, 2020 The pathogenesis of preeclampsia (PE) involves several pathophysiological processes that may be affected by glucocorticoid (GC). We confirmed previously that GC exposure could result in PE, while PE is linked to a deficiency of lipoxin A4 (LXA4), an ...
Haojing Liu +5 more
doaj +1 more source
Journal of Periodontal Research, EarlyView.This review describes the features of grade C molar‐incisor pattern periodontitis and discusses the role of A. actinomycetemcomitans in its pathogenesis and why molars and incisors are preferably affected. Possible future studies on this aggressive disease in primary and permanent dentition and emerging omics techniques for diagnosis and management are
Luigi Nibali +3 more
wiley +1 more source
Activity of topically applied leukotriene B4 in experimental dermatophytosis
, 1992 In a pilot study to assess the antimycotic potential of the chemoattractant leukotriene B4 (LTB4), guinea pigs were infected with Trichotphyton mentagrophytes var.
Shankland, G. S., Richardson, M. D.
core +2 more sources
Праці Наукового товариства імені Шевченка. Медичні науки, 2019 LEUKOTRIENE B4 AND PROSTAGLANDIN E2 LEVELS IN PATIENTS WITH NSAID-GASTROPATHY AFTER PANTOPRAZOLE ...
K. Kvit +3 more
doaj
Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence
Journal of Periodontal Research, EarlyView.This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo +3 more
wiley +1 more source
Leukotriene B4 Mediates Sphingosylphosphorylcholine-Induced Itch-Associated Responses in Mouse Skin
, 2009 In atopic dermatitis, the concentration in the skin of sphingosylphosphorylcholine (SPC), which is produced from sphingomyelin by sphingomyelin deacylase, is increased.
Saito, Ayumi +2 more
core +1 more source