Results 81 to 90 of about 29,391 (230)
Antibiotic‐mediated immune modulation in periodontitis
Periodontology 2000, EarlyView.Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
HTLV-1-induced leukotriene B4 secretion by T cells promotes T cell recruitment and virus propagation
Nature Communications, 2017 HTLV-1 predominantly spreads through direct cell-cell contacts, but mechanisms of target cell recruitment are unclear. Here, the authors show that HTLV-1 infected T-cells secrete leukotriene B4, which recruits T-cells, facilitates HTLV-1 transmissionin ...
Florent Percher +12 more
doaj +1 more source
Inhibition of LTA4H by bestatin in human and mouse colorectal cancerResearch in context
EBioMedicine, 2019 Background: Our preclinical data showed that the leukotriene A4 hydrolase (LTA4H) pathway plays a role in colorectal cancer (CRC). High expression of LTA4H and leukotriene B4 receptor type 1 (BLT1) were also associated with CRC survival probability ...
Simin Zhao +14 more
doaj +1 more source
Leukotriene receptor expression in esophageal squamous cell cancer and non-transformed esophageal epithelium: a matched case control study [PDF]
, 2016 Study questionnaire.
C. Helmke +7 more
core +2 more sources
The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy
MedComm, Volume 7, Issue 6, June 2026.Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma +6 more
wiley +1 more source
Nature Communications, 2017 Hematopoietic stem and progenitor cells are generated first from the vascular endothelium of the dorsal aorta and then the fetal liver but what regulates this switch is unknown.
Xuan Jiang +11 more
doaj +1 more source
Glucuronidation of arachidonic and linoleic acid metabolites by human UDP-glucuronosyltransferases
Journal of Lipid Research, 2003 Arachidonic acids (AA) and linoleic acids (LAs) are metabolized, in several tissues, to hydroxylated metabolites that are important mediators of many physiological and pathophysiological processes.
David Turgeon +6 more
doaj +1 more source
Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley +1 more source
Protein Science, Volume 35, Issue 6, June 2026.Abstract The leucine‐rich repeat‐containing G protein‐coupled receptor 6 (LGR6) has a potential role in inflammation resolution and different cancer processes. In this study, we employed computational techniques, including molecular docking and molecular dynamics simulations of mammalian membrane‐embeded systems, to understand the activation mechanism ...
Álex Pérez‐Sánchez +3 more
wiley +1 more source