Results 141 to 150 of about 12,649 (233)

Amino Acid and Lipid Metabolism in Cancer: Mechanisms and Therapeutic Opportunities

MedComm, Volume 7, Issue 8, August 2026.
Amino Acid and lipid metabolism in cancer: (A) Regulation of Amino acid transportation and metabolism in cancer. (B) The core organization of lipid metabolic reprogramming in cancer and their functional consequences. ABSTRACT Metabolic reprogramming is a defining feature of cancer and a major contributor to immune escape.
Zixu Wang, Xin Fu, Jingchao Bai, Yanguo Liu, Kai Huang   +4 more
wiley   +1 more source

Lymphatic Endothelial Cells in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang, Wang Lin, Hengyang Liu, Jixin Zhong, Shiliang Li, Xiaoquan Rao   +5 more
wiley   +1 more source

Straightforward Synthesis, Spectroscopic Characterizations, Molecular Docking, Molecular Dynamics Simulations, and Comprehensive DFT Calculations of Novel Tetrazole 1,5 and 2,5‐Disubstituted Tetrazole Scaffolds

ChemistryOpen, Volume 15, Issue 8, August 2026.
A series of novel 1,5‐ and 2,5‐disubstituted tetrazole heterocyclic scaffolds was synthesized and characterized by single‐crystal X‐ray diffraction. Their electronic properties were investigated using density functional theory calculations, while molecular docking and molecular dynamics simulations revealed promising biological potential and favorable ...
Riham Sghyar, Ahmed Chelouan, Brahim El Ibrahimi, Olivier Blacque, Basavarajaiah Suliphuldevara Mathada, Prashantha Karunakar, Oussama Moussaoui, Mouad Lahyaoui, Joel T. Mague, Ali Aghmiz, Manal El‐Gendy, Mohamed Hefnawy, Nada Kheira Sebbar   +12 more
wiley   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Pediatric Mild Asthma: Bridging Current Gaps to Improve Future Care

Pediatric Pulmonology, Volume 61, Issue 8, August 2026.
ABSTRACT Background Pediatric mild asthma is considered a benign condition, yet it accounts for a substantial proportion of morbidity. Characterization and management of children or adolescents with mild asthma are less explored than in adults, particularly due to its heterogeneous nature and variable course.
Francesca Santamaria, Cristina Fontanella, Melissa Borrelli   +2 more
wiley   +1 more source

Role of Leukotriene Receptor Antagonists in Asthma

Pediatrics & Neonatology, 2012
openaire   +3 more sources

A Quininib Analogue and Cysteinyl Leukotriene Receptor Antagonist Inhibits Vascular Endothelial Growth Factor (VEGF)-independent Angiogenesis and Exerts an Additive Antiangiogenic Response with Bevacizumab. [PDF]

J Biol Chem, 2017
Butler CT, Reynolds AL, Tosetto M, Dillon ET, Guiry PJ, Cagney G, O'Sullivan J, Kennedy BN.   +7 more
europepmc   +1 more source

Recurrent Spasmodic Croup‐Like Episodes With Cough‐Predominant Symptoms in an Atopic School‐Aged Child: The Importance of Integrated Upper‐ and Lower‐Airway Management

Respirology Case Reports, Volume 14, Issue 8, August 2026.
Clinical course from 2019 to 2026. Stars indicate croup episodes, the black polygons indicate cough burden, * indicates a period of increased cough burden. No recurrence of croup episodes was observed during follow‐up after February 2024. ICS, inhaled corticosteroid; INCS, intranasal corticosteroid; LABA, long‐acting β2‐agonist; LTRA, leukotriene ...
Rina Sakaguchi, Shizuka Mitsubuchi, Yusuke Miyashita, Toshihiko Nonaka, Kimitoshi Nakamura   +4 more
wiley   +1 more source

Dissociated Biologic Responses Across the United Airway: A Case Report of Severe Asthma With Chronic Rhinosinusitis With Nasal Polyps and Eosinophilic Otitis Media

Respirology Case Reports, Volume 14, Issue 8, August 2026.
We report a case of severe asthma with chronic rhinosinusitis with nasal polyps and eosinophilic otitis media that was successfully controlled by switching biologic therapy from dupilumab to mepolizumab. Careful monitoring of disease activity and consideration of biologic switching may help achieve optimal control with currently available biologics ...
Tomoko Tajiri, Naoki Takemoto, Toshiya Minakata, Motohiko Suzuki, Yoshiyuki Ozawa, Hirotsugu Ohkubo   +5 more
wiley   +1 more source

Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 4, Page 494-504, August 2026.
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang, Teng‐Fei Li, Tian‐Yu Wang, Huan‐Hai Liu   +3 more
wiley   +1 more source