Results 221 to 230 of about 354,007 (274)
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Allergy, 2001
Cysteinyl leukotrienes, synthesized de novo from cell membrane phospholipids, are proinflammatory mediators that play an important role in the pathophysiology of asthma. These mediators are among the most potent of bronchoconstrictors and cause vasodilation, increased microvascular permeability, exudation of macromolecules and edema.
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Cysteinyl leukotrienes, synthesized de novo from cell membrane phospholipids, are proinflammatory mediators that play an important role in the pathophysiology of asthma. These mediators are among the most potent of bronchoconstrictors and cause vasodilation, increased microvascular permeability, exudation of macromolecules and edema.
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The leukotriene receptor antagonist montelukast and its possible role in the cardiovascular field
European Journal of Clinical Pharmacology, 2017M. Hoxha, G. Rovati, A. B. Cavanillas
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Role of Leukotrienes and Leukotriene Receptor Antagonists in Asthma
Pulmonary Pharmacology & Therapeutics, 1999T R, Jones, I W, Rodger
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Role of leukotriene receptor antagonists in pediatric asthma
Pediatric Pulmonology, 2000During the past decade, the inflammatory mechanisms that result in the clinical syndrome we call asthma have been emphasized in research, publications, and the various asthma management guidelines. This information clearly emphasizes the treatment of asthma with maintenance controller therapies early after the onset of symptoms in all but the very ...
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Naunyn-Schmiedeberg's Archives of Pharmacology, 2013
I. T. Abdel-Raheem, Naglaa F. Khedr
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I. T. Abdel-Raheem, Naglaa F. Khedr
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European Journal of Cardio-Thoracic Surgery, 2013
F. Al-amran, N. Hadi, A. M. Hashim
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F. Al-amran, N. Hadi, A. M. Hashim
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Drugs under experimental and clinical research, 1989
A series of chlorophenoxyalkyl acids were prepared and evaluated as pharmacological antagonists of leukotriene D4. Structure-activity relationship studies pointed to LY137617 as a compound with possible therapeutic value. In experiments on isolated smooth muscles from the guinea-pig, this agent was a selective and moderately potent antagonist of ...
D K, Herron +5 more
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A series of chlorophenoxyalkyl acids were prepared and evaluated as pharmacological antagonists of leukotriene D4. Structure-activity relationship studies pointed to LY137617 as a compound with possible therapeutic value. In experiments on isolated smooth muscles from the guinea-pig, this agent was a selective and moderately potent antagonist of ...
D K, Herron +5 more
openaire +1 more source