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Pharmacology of leukotriene receptor antagonists
American journal of respiratory and critical care medicinePreclinical pharmacological studies have demonstrated that cysLT1 receptor antagonists, such as zafirlukast, montelukast, and pobilukast, are potent and selective antagonists of cysteinyl leukotriene (cysLT) activity. In vitro, these agents compete with [3H]LTD4 for binding to cysLT1 receptors present on guinea pig and human lung cell membranes.
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A placebo-controlled, dose-ranging study of montelukast, a cysteinyl leukotriene–receptor antagonist
Journal of Allergy and Clinical Immunology, 1998T F Reiss, Theodore F Reiss, L C Altman
exaly
American Journal of Respiratory and Critical Care Medicine, 1999
T. Pullerits +4 more
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T. Pullerits +4 more
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Bronchoprotective Effects of Leukotriene Receptor Antagonists in AsthmaA Meta-analysis
Chest, 2002Graeme P Currie, Brian Lipworth
exaly

