Results 61 to 70 of about 12,649 (233)

Data on various allergen specific IgEs and prospective treatments on food-dependent exercise-induced anaphylaxis

open access: yesData in Brief, 2018
Food-dependent exercise-induced anaphylaxis (FDEIAn) is an anaphylactic reaction induced by physical exercise after ingestion of certain meals. FDEIAn is not very frequent, but recent case reports associated with various meals indicate an upward trend ...
Norihide Murayama, Kikuno Murayama
doaj   +1 more source

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta   +9 more
wiley   +1 more source

Exercise-induced bronchoconstriction: The effects of montelukast, a leukotriene receptor antagonist

open access: yesTherapeutics and Clinical Risk Management, 2009
James P KempClinical Professor of Pediatrics, Division of Immunology and Allergy, University of California School of Medicine, San Diego, CA, USAAbstract: Exercise-induced bronchoconstriction (EIB) is very common in both patients with asthma and those ...
James P Kemp
doaj  

Intermittent and episode-driven use of pranlukast to reduce the frequency of wheezing in atopic children: a randomized, double-blind, placebo-controlled trial

open access: yesWorld Allergy Organization Journal, 2015
Background Leukotriene receptor antagonist (LTRA) therapy reduces asthma exacerbations in children older than 2 years. However, whether early intervention using LTRA in atopic smaller children aged 1 to 2 years who had experienced episodic wheezing can ...
Motohiro Ebisawa   +8 more
doaj   +1 more source

Enhanced Early Detection of Allergic Rhinitis: A Prospective Study on a Symptom‐Based Predictive Model

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Allergic rhinitis (AR) and non‐allergic rhinitis (NAR) share overlapping symptoms but differ in pathophysiology and treatment. Current AR diagnosis relies on skin prick testing (SPT) and serum IgE quantification, both of which are complex.
Ke‐Zhang Zhu   +4 more
wiley   +1 more source

The management of adults and children with moderate severity asthma

open access: yesSouth African Family Practice, 2007
Moderate severity asthma occurs in approximately 10 to 15% of patients with chronic reversible airway obstruction and is defined by more than four daytime symptoms per week, more than four night time symptoms per month and peak expiratory flow rates of ...
P.M. Jeena
doaj   +1 more source

Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress

open access: yesIntegrative Zoology, EarlyView.
Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu   +5 more
wiley   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

open access: yesAllergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller   +16 more
wiley   +1 more source

Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer

open access: yesFrontiers in Cell and Developmental Biology, 2016
Colorectal cancer is the third most common cancer worldwide and is associated with significant morbidity and mortality. Current pharmacotherapy options include cytotoxic chemotherapy, anti-VEGF and anti-EGFR targeting drugs, but these are limited by ...
Lorraine Burke   +7 more
doaj   +1 more source

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