Results 91 to 100 of about 100,641 (375)

Long‐term safety and efficacy of levodopa‐carbidopa intestinal gel in advanced Parkinson's disease

open access: yesMovement Disorders, 2018
Background: Levodopa‐carbidopa intestinal gel (designated as carbidopa‐levodopa enteral suspension in the United States) provides stable plasma levodopa concentrations and reduces motor fluctuations in advanced Parkinson's disease patients through ...
H. Fernandez   +15 more
semanticscholar   +1 more source

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

open access: yesBMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim   +5 more
wiley   +1 more source

Intrastriatal Memantine Infusion Dampens Levodopa-Induced Dyskinesia and Motor Deficits in a Mouse Model of Hemiparkinsonism

open access: yesFrontiers in Neurology, 2019
Although the administration of dopamine precursor levodopa remains as the mainstay for the treatment of Parkinson's disease, long-term exposure to levodopa often causes a disabling complication, referred to as levodopa-induced dyskinesias. Therefore, the
Masatoshi Ogawa   +9 more
doaj   +1 more source

Levodopa‐Induced Neuropathy: A Systematic Review

open access: yesMovement Disorders Clinical Practice, 2018
Clinical, neurophysiological, and pathological evidence suggest an association between Parkinson's disease (PD) and peripheral neuropathy (PNP), with a possible causative role of levodopa metabolic products, such as homocysteine and methylmalonic acid.
A. Romagnolo   +5 more
semanticscholar   +1 more source

Toward personalized healthcare: Advances in two‐dimensional nanomaterial‐based flexible electrochemical sensors for physiological monitoring

open access: yesBMEMat, EarlyView.
This review provides an overview of the properties, composites and application of two‐dimensional (2D) nanomaterials for wearable electrochemical biosensors. Also, the challenges and future prospects of utilizing 2D nanomaterials in wearable electrochemical biosensor applications are discussed.
Kou Zhang   +8 more
wiley   +1 more source

Extended-release oral capsule of carbidopa–levodopa in Parkinson disease

open access: yesTherapeutic Advances in Neurological Disorders, 2018
Motor fluctuations complicate the treatment of patients with Parkinson’s disease receiving levodopa. Extended-release carbidopa–levodopa has a pharmacokinetic profile that provides a more continuous levodopa serum concentration.
Jason Margolesky, Carlos Singer
doaj   +1 more source

Treatment initiation for parkinson’s disease in Australia 2013–2018: a nation-wide study

open access: yesBMC Geriatrics, 2022
Background Guidelines highlight the importance of an individualized approach to treatment initiation for Parkinson’s disease. Our aim was to investigate initiation of anti-Parkinson medication in Australia from 2013–2018, and to determine factors ...
Marjaana Koponen   +5 more
doaj   +1 more source

Tocotrienols: A Review From Source to Therapeutic Applications

open access: yesFood Frontiers, EarlyView.
Tocotrienols demonstrate superior antioxidant, neuroprotective, and anti‐inflammatory properties compared to conventional vitamin E forms, with promising therapeutic applications across multiple disorders when delivered through optimized systems that enhance their inherently limited bioavailability.
Natalia‐Carolina Londoño   +6 more
wiley   +1 more source

Effect of Rectal Levodopa Administration: A Case Report

open access: yesCase Reports in Neurology, 2015
Objective: The aim of this report is to discuss whether or not rectal levodopa administration is useful in some situations. Background: In situations where oral intake of levodopa formulations is not possible, the treatment options of Parkinson's disease
Jolanda M.J. Vogelzang   +2 more
doaj   +1 more source

Orthostatic stability with intravenous levodopa [PDF]

open access: yesPeerJ, 2015
Intravenous levodopa has been used in a multitude of research studies due to its more predictable pharmacokinetics compared to the oral form, which is used frequently as a treatment for Parkinson’s disease (PD).
Shan H. Siddiqi   +2 more
doaj   +2 more sources

Home - About - Disclaimer - Privacy