Results 61 to 70 of about 95,577 (390)

Chitosan-Coated Hydroxypropylmethyl Cellulose Microparticles of Levodopa (and Carbidopa): In Vitro and Rat Model Kinetic Characteristics

Current Therapeutic Research, 2020
: Background: Parkinson's disease is a neurodegenerative disorder, and a major cause of disability. Levodopa, a prodrug of dopamine, remains the gold standard in the pharmacological management of Parkinson's disease.
Benedicta Obenewaa Dankyi, MPhil, Seth Kwabena Amponsah, PhD, Grace Lovia Allotey-Babington, PhD, Ismaila Adams, BPharm, Nana Aboadwe Goode, BPharm, Henry Nettey, PharmD/PhD   +5 more
doaj  

Dopa-responsive dystonia and hyperprolactinaemia : a novel association in two sisters [PDF]

, 2007
Dopa-Responsive Dystonia (DRD) is a rare hereditary condition of childhood-onset dystonia which responds dramatically to treatment with levodopa. It was first described in 1971 as a "hereditary progressive basal ganglia disease with marked diurnal ...
Cachia, Mario J., Galea, Janabel
core  

Impulse control disorders in Parkinson's disease: decreased striatal dopamine transporter levels [PDF]

, 2013
Objective Impulse control disorders are commonly associated with dopaminergic therapy in Parkinson's disease (PD). PD patients with impulse control disorders demonstrate enhanced dopamine release to conditioned cues and a gambling task on [11C]raclopride
A. Rizos, Ahlskog, Chernoloz, Cilia, Crits-Christoph, Evans, Evans, G. Vivian, Grace, Guttman, Harden, Innis, Jacobsen, K. Ray Chaudhuri, Laine, Laruelle, Malison, McCann, N. A. Howell, N. Harrison, N. Mulholland, Nirenberg, O'Sullivan, R. Chakravartty, Rabinak, Ray, S. Robinson, Schmitt, Schneider, Sekine, Steeves, Steeves, Sulzer, Sulzer, Tomlinson, V. Voon, Vallelunga, Volkow, Volkow, Voon, Voon, Voon, Voon, Weintraub   +43 more
core   +1 more source

Nanomaterial‐Enhanced Biosensing: Mechanisms and Emerging Applications

Advanced Healthcare Materials, EarlyView.
Nanomaterial integration transforms biosensor capabilities through enhanced signal transduction, sensitivity, and selectivity. This review analyzes how nanoscale materials—from nanoparticles to nanosheets—leverage unique physicochemical properties to revolutionize electrochemical, optical, and electrical biosensing.
Younghak Cho, Yunyoung Choi, Yerim Jang, Hyejeong Seong   +3 more
wiley   +1 more source

Expanding the spectrum of impulse control disorders in Parkinson's disease: the phenomenology of sweet craving [PDF]

, 2013
Thesis (M.A.)--Boston UniversityBackground: The recognized spectrum of impulse control disorders in Parkinson’s disease (PD) includes pathologic gambling, hypersexuality, compulsive buying, and binge eating, and is commonly related to exposure to ...
Brown, Caitlin Harrington
core   +1 more source

Toward understanding ambulatory activity decline in Parkinson disease [PDF]

, 2015
BACKGROUND: Declining ambulatory activity represents an important facet of disablement in Parkinson disease (PD). OBJECTIVE: The primary study aim was to compare the 2-year trajectory of ambulatory activity decline with concurrently evolving facets of ...
Cavanaugh, James T., Dibble, Leland E., Earhart, Gammon M., Ellis, Terry D., Ford, Matthew P., Foreman, K. Bo   +5 more
core   +1 more source

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

Advanced Materials, EarlyView.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis, Subhajit Dutta, Saqib Kamal, Sergio Gómez‐Graña, Isabel Pastoriza‐Santos, Stefan Wuttke, Lakshminarayana Polavarapu   +6 more
wiley   +1 more source

Rasagiline as Adjunct to Levodopa for Treatment of Parkinson’s Disease: A Systematic Review and Meta-Analysis

Parkinson's Disease, 2022
Background. Rasagiline is a selective, irreversible monoamine oxidase type B inhibitor used as monotherapy in early Parkinson’s disease and as an adjunct therapy to levodopa in Parkinson’s disease with motor fluctuations. Objectives.
Osamu Kano, Hiroshi Tsuda, Ayako Hayashi, Masaki Arai   +3 more
doaj   +1 more source

Long‐term safety and efficacy of levodopa‐carbidopa intestinal gel in advanced Parkinson's disease

Movement Disorders, 2018
Background: Levodopa‐carbidopa intestinal gel (designated as carbidopa‐levodopa enteral suspension in the United States) provides stable plasma levodopa concentrations and reduces motor fluctuations in advanced Parkinson's disease patients through ...
H. Fernandez, J. Boyd, V. Fung, M. Lew, R. Rodriguez, J. Slevin, D. Standaert, C. Zadikoff, A. Vanagunas, K. Chatamra, S. Eaton, M. Facheris, Coleen M Hall, W. Robieson, J. Benesh, A. Espay   +15 more
semanticscholar   +1 more source

Progress in Flexible Perovskite Solar Cells: Paving the Way for Scalable Manufacturing

Advanced Materials Technologies, EarlyView.
Perovskite solar cells (PSCs) are well positioned for a successful market uptake. This is due to an unprecedented improvement of their efficiency and stability since the first report in 2009. In this review paper, the building blocks for the scalable manufacturing and future commercialization of flexible PSCs and their pathway to impact will be ...
Dimitar I. Kutsarov, Ehsan Rezaee, Jed Lambert, Walter Tevis Stroud, Apostolos Panagiotopoulos, S. Ravi P. Silva   +5 more
wiley   +1 more source