Results 11 to 20 of about 62,519 (222)

Levofloxacin-Associated Neurotoxicity in a Patient with a High Concentration of Levofloxacin in the Blood and Cerebrospinal Fluid

Antibiotics, 2019
Neurotoxicity is a rare and intolerable adverse effect associated with levofloxacin therapy, whose diagnosis has mostly been reported based on medical history rather than quantitative measures in the blood.
Masashi Nishikubo, Hiroaki Nishioka
exaly   +4 more sources

Levofloxacin and Rifampin Resistance in Helicobacter pylori Isolates from Central-Western Colombia: Role of gyrA Mutations in Fluoroquinolone Resistance [PDF]

Antibiotics
Background: Helicobacter pylori causes one of the most prevalent chronic bacterial infections worldwide. Data about H. pylori resistance rates to levofloxacin and rifampin (antimicrobials for second-, third- or fourth-line therapy) in Colombia and South ...
Adalucy Álvarez-Aldana, Leonardo Beltrán-Angarita, Yina Marcela Guaca-González, Manuel Alejandro Velandia-López, Lyudmila Boyanova   +4 more
doaj   +2 more sources

TXA11114: Discovery of an In Vivo Efficacious Efflux Pump Inhibitor (EPI) That Potentiates Levofloxacin Against Pseudomonas aeruginosa [PDF]

Antibiotics
Objectives: Multidrug-resistant (MDR) Pseudomonas aeruginosa represents a major clinical challenge, driven in part by resistance–nodulation–division (RND) efflux pumps that reduce intracellular antibiotic concentrations and limit the efficacy of many ...
Jesus D. Rosado-Lugo, Pratik Datta, Ahmad Altiti, Yongzheng Zhang, Jun Lu, Yi Yuan, Ajit K. Parhi   +6 more
doaj   +2 more sources

The efficacy and safety of nemonoxacin compared with levofloxacin in the treatment of community-acquired pneumonia: a systemic review and meta-analysis of randomized controlled trials

Infection and Drug Resistance, 2019
Shen-Peng Chang,1 Hong-Zin Lee,2 Chih-Cheng Lai,3 Hung-Jen Tang4 1Department of Pharmacy, Chi Mei Medical Center, Liouying, Taiwan; 2School of Pharmacy, China Medical University, Taichung, Taiwan; 3Department of Intensive Care Medicine, Chi Mei Medical ...
Chang SP, Lee HZ, Lai CC, Tang HJ
doaj   +1 more source

PRODUCTION AND INVESTIGATION OF PROPERTIES OF LIPOSOMAL LEVOFLOXACIN

Тонкие химические технологии, 2013
Liposomal levofloxacin was prepared with the extrusion technique. Levofloxacin is a fluoroquinolone used for resistant tuberculosis treatment. Traditional lipids such as phosphatidylcholine (PC), as well as a mixture of PC and cholesterol (Chol) were ...
G. М. Sorokoumova, Ya. O.H. Yasin, Ju. L. Mikulovich, T. G. Smirnova, S. N. Andreevskaya, А. А Selischeva, L. N. Chernousova, V. I. Shvets   +7 more
doaj   +1 more source

Comparison of high-dose, short-course levofloxacin treatment vs conventional regimen against acute bacterial infection: meta-analysis of randomized controlled trials

Infection and Drug Resistance, 2019
Chih-Wei Chen,1,2 Yu-Hung Chen,3 I-Ling Cheng,3 Chih-Cheng Lai41Division of Neurosurgery, Department of Surgery, Chi Mei Medical Center, Tainan, Taiwan; 2Department of Occupational Safety and Health, Institute of Industrial Safety and Disaster Prevention,
Chen CW, Chen YH, Cheng IL, Lai CC
doaj   +1 more source

Update on the second-line treatment of infection: a narrative review

Therapeutic Advances in Gastroenterology, 2023
A standard bismuth quadruple therapy, a fluoroquinolone-containing triple (or quadruple) therapy or a proton pump inhibitor (PPI)-amoxicillin high-dose dual therapy has been recommended as a second-line treatment for Helicobacter pylori infection by the ...
Chih-An Shih, Chang-Bih Shie, Wei-Chen Tai, Seng-Kee Chuah, Hsi-Chang Lee, Ping-I Hsu   +5 more
doaj   +1 more source

Antibiotic resistance of Helicobacter pylori in the European part of the Russian Federation: first results [PDF]

Терапевтический архив, 2020
Aim. Determine the primary antibiotic resistance of Helicobacter pylori (H. pylori) strains isolated from patients living in the European part of the Russian Federation. Materials and methods. As part of a clinical laboratory study, from 2015 to 2018,
I. V. Maev, D. N. Andreev, V. M. Govorun, E. N. Ilina, Yu. A. Kucheryavyy, T. S. Oganesian, E. V. Melnikova, O. V. Zayratyants, T. V. Parfenova, L. V. Dzhedzheia, N. V. Kirillova, E. A. Maevskaya, A. K. Fomenko, E. G. Lobanova, A. V. Zaborovskii, K. A. Kriukov   +15 more
doaj   +1 more source

Synthesis a Number of Heterocyclic Compounds and some of chalcones Derived From Levofloxacin

Tikrit Journal of Pure Science, 2023
The hydrazide (1) was used as synthone for the following Compound pyridazine-3,6-dione (2) by reaction of hydrazide (1) with maleic  anhydride and Compound phthalazine-1,4-dione (3) by the reaction of  hydrazide (1) with phthalic anhydride.
Ekram Abdullah Basheer, Kalid Matny Al-jaanaby, Feras Shauki Al-joboury   +2 more
doaj   +1 more source

Susceptibility-Guided Versus Empirical Therapy for Helicobacter pylori Infection in a High Resistance Setting: A Randomised Controlled Trial. [PDF]

Microbiologyopen
In a randomised trial conducted in a high‐resistance region, PCR‐based susceptibility‐guided therapy showed no superiority over empirical therapy for Helicobacter pylori eradication. Empirical clarithromycin‐containing quadruple therapy remained effective despite high clarithromycin resistance.
Lu K, Zou X, Lang C, Zang L, Yang X, Sang W, Wang J, Feng Q, Mu Y, Liu L, Xu C, Zhao J.   +11 more
europepmc   +2 more sources