Results 31 to 40 of about 62,519 (222)

Tetracycline- levofloxacin versus amoxicillin- levofloxacin quadruple therapies in the second- line treatment of Helicobacter pylori infection

, 2021
BackgroundThe Maastricht V/Florence Consensus Report recommends amoxicillin- fluoroquinolone triple or quadruple therapy as a second- line treatment for Helicobacter pylori infection.
Huay‐Min Wang, Deng‐Chyang Wu, Chang‐Bih Shie, Ping‐I Hsu, Tsay, Feng‐woei, Chuah, Seng‐kee, Yan‐Hua Chen, Chen, Yan‐hua, Wu, I‐ting, Feng‐Woei Tsay, Tang, Sheng‐yeh, Hsu, Ping‐i, Sung‐Shuo Kao, Kuo, Chao‐hung, I‐Ting Wu, Wang, Huay‐min, Shie, Chang‐bih, Kao, Sung‐shuo, John Y. Kao, Sheng‐Yeh Tang, Wu, Deng‐chyang, Kao, John Y., Chao‐Hung Kuo, Peng, Nan‐jing, Nan‐Jing Peng, Seng‐Kee Chuah   +25 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Temperature-dependent Specific Transport of Levofloxacin in Human Intestinal Epithelial LS180 Cells [PDF]

, 2009
It was reported previously that specific levofloxacin uptake in Caco- 2 cells was inhibited by nicotine, enalapril, L-carnitine and fexofenadine. The aim of the present study was to characterize the cellular uptake of levofloxacin using another human ...
KAYANO, Yuichiro, MASAGO, Miki, ISHIDA, Kazuya, HASHIMOTO, Yukiya, FUKUMORI, Shiro, TAGUTHI, Masato   +5 more
core  

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Development and Validation of Multiplex Quantitative PCR Assay for Detection of Helicobacter pylori and Mutations Conferring Resistance to Clarithromycin and Levofloxacin in Gastric Biopsy [Corrigendum]

Infection and Drug Resistance, 2023
Binmaeil H, Hanafiah A, Mohamed Rose I, Raja Ali RA. Infect Drug Resist. 2021;14:4129–4145. The authors have advised that Table 1 on page 4132 is incorrect.
Binmaeil H, Hanafiah A, Mohamed Rose I, Raja Ali RA   +3 more
doaj  

Efficacy of levofloxacin, amoxicillin and a proton pump inhibitor in the eradication of Helicobacter pylori in Brazilian patients with peptic ulcers

Clinics, 2015
OBJECTIVES: The eradication of Helicobacter (H.) pylori allows peptic ulcers in patients infected with the bacteria to be cured. Treatment with the classic triple regimen (proton pump inhibitor, amoxicillin and clarithromycin) has shown decreased ...
Fernando Marcuz Silva, Elaine Cristina Silveira de Queiroz, Tomás Navarro-Rodriguez, Ricardo Correa Barbuti, Rejane Mattar, Kiyoshi Iriya, Jin Hwa Lee, Jaime Natan Eisig   +7 more
doaj   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Trends in Outpatient Prescribing Patterns for Ocular Topical Anti-Infectives in Six Major Areas of China, 2013–2019

Antibiotics, 2021
Topical anti-infectives are important in the management of ocular infections, but little is known about their current status and trends in their use in China. Thus, we carried out a prescription-based, cross-sectional study using the database of Hospital
Zhenwei Yu, Jianping Zhu, Jiayi Jin, Lingyan Yu, Gang Han   +4 more
doaj   +1 more source

Interfacial Proton‐Relay Microenvironment Enables Self‐Driven Singlet Oxygen Generation under Neutral Conditions

Advanced Science, EarlyView.
An interfacial proton‐relay microenvironment at MoS2‐CuCl heterostructures enables selective O2 activation to 1O2 under neutral conditions. Electron‐deficient sulfur sites mediate proton transfer to Cu‐bound O2, accelerating *OOH hydrogenation while suppressing O─O bond cleavage, achieving stable, efficient pollutant removal.
Qiaoyu Gao, Xiaohui Dai, Jian Ye, Lili Li, Chenxiao Yu, Yuehan Jiang, Jiangdong Dai, Xiaohua Tian, Jun Zhao, Jianming Pan   +9 more
wiley   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source