Results 51 to 60 of about 67,065 (238)

Mutations in the Antibiotic Target Genes Related to Clarithromycin, Metronidazole and Levofloxacin Resistance in Helicobacter pylori Strains from Children in China

Infection and Drug Resistance, 2020
Yanyi Zhang, Yi Wen, Qiulin Xiao, Wei Zheng, Gao Long, Bo Chen, Xiaoli Shu, Mizu Jiang Department of Gastroenterology, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou ...
Zhang Y, Wen Y, Xiao Q, Zheng W, Long G, Chen B, Shu X, Jiang M   +7 more
doaj  

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Microbiota Transplantation Effectively Treats Immune Checkpoint Inhibitor‐Associated Colitis: A Multi‐Center, Retrospective Case Series

Microbiota Medicine Research, EarlyView.
ABSTRACT Background Immune‐mediated colitis is an adverse effect of therapy with immune checkpoint inhibitors (ICIs). This study aims to evaluate the efficacy and safety of washed microbiota transplantation (WMT) in patients with ICI‐associated colitis.
Mengyu Huang, Yaping Liu, Hong Lu, Weihong Wang, Huiying Gao, Junlan Qiu, Yan Jin, Qian Ren   +7 more
wiley   +1 more source

Determination of embryotoxic effects of levofloxacin exposure by the in ovo method [PDF]

Eurasian Journal of Veterinary Sciences
Levofloxacin is a broad-spectrum antibacterial drug in the fluoroquinolone class that is classified as category C during pregnancy. This study aimed to determine the effects of levofloxacin administration on embryos at different developmental stages.
Rahmi Canbar, Osman Dagar, Tugba Melike Parlak, Mehmet Tuzcu, Enver Yazar   +4 more
doaj  

Levofloxacin loaded PMMA:PVP blended nanofiber mat as an antibacterial material

Materials Research Express
Polymeric nanofibers loaded with antibacterial agents occupy a leading position among many technologies for producing antibacterial materials due to their unique properties.
V A Karachevtsev, A M Plokhotnichenko, O V Trufanov, S G Stepanian   +3 more
doaj   +1 more source

Maximizing Pharmacodynamics with High-Dose Levofloxacin

, 2005
Objective To review published literature of levofloxacin 750 mg for the treatment of community-acquired pneumonia (CAP), nosocomial-acquired pneumonia (NAP), and skin and skin-structure infections (SSSI) focusing on microbiology, pharmacokinetic, and ...
Nichole A. Wargo, Edward H. Eiland, Kurt A. Wargo   +2 more
core   +1 more source

Photo‐responsive carbon dots for pyroptosis‐mediated anti‐tumor application

Responsive Materials, EarlyView.
Photo‐responsive CDs generate ROS to induce tumor cell pyroptosis, thereby stimulating antitumor immunity. Abstract Pyroptosis refers to a kind of lytic programmed cell death, characterized by the release of pro‐inflammatory cytokines during the process. Owing to its immune response stimulation ability, pyroptosis has garnered considerable attention in
Lingyun Li, Xue Wu, Zekun Yan, Jun Wu, Caishi Huang, Songnan Qu   +5 more
wiley   +1 more source

Molecular and proteomic analysis of levofloxacin and metronidazole resistant Helicobacter pylori

Frontiers in Microbiology, 2016
Antibiotic resistance in bacteria incur fitness cost, but compensatory mechanisms may ameliorate the cost and sustain the resistance even under antibiotics-free conditions.
Aimi Hanafi, Woon Ching Lee, Mun Fai Loke, Mun Fai Loke, Xinsheng Teh, Ain Shaari, Mojdeh Dinarvand, Philippe Lehours, Francis Mégraud, Francis Mégraud, Alex Hwong Ruey Leow, Jamuna Vadivelu, Khean Lee Goh   +12 more
doaj   +1 more source

Carbon dots in electrochemiluminescence: Mechanisms, interface engineering, and bioanalytical applications

Responsive Materials, EarlyView.
Carbon dots are emerging as versatile electrochemiluminescent nanomaterials whose structure, surface states, and interfacial design jointly determine ECL pathways and performance. This review highlights how mechanistic understanding and materials engineering enable programmable CD‐ECL systems for bioanalysis, imaging, and future intelligent analytical ...
Yuhan Zhao, Zixuan Chen, Jun‐Jie Zhu
wiley   +1 more source

Phase I Study of Levofloxacin, (S)-(-)-Ofloxacin [PDF]

, 1992
Phase I study of levofloxacin, an optically active isomer of ofloxacin, was conducted in 21 normal healthy male volunteers. In the single-dose studies, levofloxacin was orally administered at doses of 50, 100, and 200mg after breakfast.
Okazaki, Osamu, Hakusui, Hideo, 中島, 光好, 植松, 俊彦, 金丸, 光隆   +4 more
core   +1 more source