Results 81 to 90 of about 1,731,278 (307)

Expression of ABH and Lewis antigens in chronic gastritis and pre-neoplasic alterations in gastric mucosa

, 2002
BACKGROUND:The major cause for chronic gastritis in human is the infection by the Helicobacter pylori. The blood group antigens present at the gastric mucous are described as possible receptor for this bacteria in the epithelium.
Araújo, Marialva, ASSUMPÇÃO, Mônica Baraúna de, Cruz, Ermelinda Moutinho da, ARAÚJO, Marialva Tereza Ferreira de, DAIBES, Samiry, CRUZ, Ermelinda do Rosário Moutinho da, CORVELO, Tereza Cristina de Oliveira, Corvelo, Tereza Cristina Oliveira, AGUIAR, Délia Cristina Figueira   +8 more
core   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

PEPITEM Regulates the Synovial Microenvironment During Immune‐Mediated Inflammatory Arthritis to Limit Disease

Arthritis &Rheumatology, EarlyView.
Objective Here we investigate the status of the adiponectin–PEPITEM pathway in early, treatment naive rheumatoid arthritis (RA) and psoriatic arthritis (PsA) and the therapeutic efficacy of PEPITEM administration in preclinical models. Methods Peripheral blood was isolated from patients with clinical suspect arthralgia and suspected inflammatory ...
Mussarat Wahid, Samuel Kemble, Oladimeji Abudu, Anella Saviano, Christopher Mahony, Jonathan W. Lewis, Thomas A. Nicholson, Anna Schettino, Noemi Marigliano, Kathryn Frost, Jenefa Begum, Alyssa M. Urbanowski, Marion Limo, Rakesh Jha, Sandra Martinez Jarquin, Laleh Pezhman, Abbie E. A. Degan, Amy E. Anderson, Charlotte G. Smith, Armaiti Batki, Holly Adams, Francesco Caso, Raffaele Scarpa, Iain McInnes, Stefan Siebert, Arthur G. Pratt, Andrew Filer, Karim Raza, Adam P. Croft, Myriam Chimen, Felicity de Cogan, G. Ed Rainger, Asif J. Iqbal, Francesco Maione, Helen M. McGettrick   +34 more
wiley   +1 more source

Simultaneous expression of type 1 and type 2 lewis blood group antigens byhelicobacter pylorilipopolysaccharides

, 1998
Previous structural investigations performed on the lipopolysaccharides (LPSs) from the human gastric pathogen Helicobacter pylori have revealed that these cell surface glycan molecules express type 2 partially fucosylated, glucosylated, or ...
Blaser, Martin J., Zheng, P. Y., Wirth, Hans-Peter, Yang, Manqiao, Appelmelk, Ben J., Rasko, David A., Moran, Anthony P., Monteiro, Mario A., Chan, Kenneth H. N., Taylor, Diane E., Hynes, Sean O., Perry, Malcolm B.   +11 more
core   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

Histo-Blood Group Antigens in Children with Symptomatic Rotavirus Infection

Viruses, 2019
Group A rotaviruses are a major cause of acute gastroenteritis in children. The diversity and unequal geographical prevalence of rotavirus genotypes have been linked to histo-blood group antigens (HBGAs) in different human populations.
Raúl Pérez-Ortín, Susana Vila-Vicent, Noelia Carmona-Vicente, Cristina Santiso-Bellón, Jesús Rodríguez-Díaz, Javier Buesa   +5 more
doaj   +1 more source

Solution structure of two xeno-antigens: aGal-LacNAc and aGal-Lewis X [PDF]

, 2002
Organ hyperacute rejection, a phenomenon occurring during discordant xenotransplantation, is due to the recognition of an oligosaccharide epitope by human xenoreactive natural antibodies.
Du Penhoat, C.H., Corzana, F. [0000-0001-5597-8127], Bovin, N.V., Tyrtysh, T.V., Imberty, A., Bettler, E.   +5 more
core  

Lewis x Antigen is Associated to Head and Neck Squamous Cell Carcinoma Survival [PDF]

, 2022
Head and neck squamous cell carcinoma (HNSCC) is an aggressive disease with poor prognosis without appropriate prognostic markers. Previous research shows that Lewis antigens have been involved in carcinoma dissemination and patients´ survival.
Segal-Eiras, Amada, Pereyra, Adrián, Abba, Martín Carlos, Rabassa, Martín Enrique, Pereyra, Liliana, Croce, María Virginia   +5 more
core  

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Helicobacter pylori lipopolysaccharide modification, Lewis antigen expression, and gastric colonization are cholesterol-dependent

BMC Microbiology, 2009
Background Helicobacter pylori specifically takes up cholesterol and incorporates it into the bacterial membrane, yet little is currently known about cholesterol's physiological roles. We compared phenotypes and in vivo colonization ability of H.
McGee David J, Hildebrandt Ellen
doaj   +1 more source