Results 101 to 110 of about 1,731,278 (307)

Diagnosis of Acute Hemolytic Transfusion Reaction Caused by Cold Reactive Anti‐P1 Antibody: A Case Report

iLABMED, EarlyView.
A 65‐year‐old patient developed acute hemolytic transfusion reaction (AHTR) after receiving P1‐positive red blood cells. The causative anti‐P1 antibody was detectable only at 4°C, evading routine 37°C pre‐transfusion screening. This case highlights that in patients with a repeated transfusion history, dual‐temperature serological testing (37°C and 4°C)
Ke Song, Chunya Ma, Wenjia Zhang, Shilan Gao, Xin Zhang, Wei Yang, Yang Yu   +6 more
wiley   +1 more source

The prevalence of secretor status and co-expression of lewis antigen in voluntary blood donors

Asian Journal of Medical Sciences, 2016
Background: Blood group substances are present in soluble form in a majority of individuals in secretion such as saliva and body fl uids. Secretor status refers to the presence (SeSe and Sese) or absence (sese) of secretor gene which secrete ABH ...
R Raj Bharath
doaj   +1 more source

Molecular basis for Lewis alpha (1, 3/1, 4)-fucosyltransferase gene deficiency (FUT3) found in Lewis-negative Indonesian pedigrees.

, 1994
The Le(a) and Le(b) human blood group antigens are synthesized in tissues producing exocrine secretions; they also circulate in plasma, where they are adsorbed by erythrocytes.
Watt, Julie, Aziz, Auda, Mollicone, Rosella, Fletcher, Anne, Reguigne, Isabelle, Lowe, John, Cameron, H, Weston, Brent, Kelly, Robert, Chatfield, Sue   +9 more
core   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

c‐Met‐Targeted Imaging Agents: Progress and Challenges

iRADIOLOGY, EarlyView.
This review summarizes recent advances in c‐Met‐targeted imaging probes, including hepatocyte growth factor (HGF) ligands, antibodies, peptides, and small molecules across magnetic resonance imaging (MRI), positron emission tomography (PET), single‐photon emission computed tomography (SPECT), and optical imaging modalities.
Yonghao Li, Aiyan Ji, Qihang Ding, Hongyue Lou, Zhen Cheng   +4 more
wiley   +1 more source

Helicobacter pylori adhesion to gastric epithelial cells is mediated by glycan receptors

Brazilian Journal of Medical and Biological Research, 2010
Helicobacter pylori adhesion to gastric epithelial cells constitutes a key step in the establishment of a successful infection of the gastric mucosa. The high representation of outer membrane proteins in the bacterial genome suggests the relevance of ...
A. Magalhães, C.A. Reis
doaj  

Synergistic Effects of Metal–Organic Nanoplatform and Guanine Quadruplex-Based CpG Oligodeoxynucleotides in Therapeutic Cancer Vaccines with Different Tumor Antigens

Vaccines
Oligodeoxynucleotides (ODNs) containing unmethylated cytosine–phosphate–guanosine (CpG) motifs are readily recognized by Toll-like receptor 9 on immune cells, trigger an immunomodulatory cascade, induce a Th1 -biased immune milieu, and have great ...
Xia Li, Mitsuhiro Ebara, Naoto Shirahata, Tomohiko Yamazaki, Nobutaka Hanagata   +4 more
doaj   +1 more source

Studies on in vitro human T cell reactivity to antigens of mycobacterium tuberculosis

, 2010
Studies on Mycobacterium tuberculosis (MTB) antigens are important to improve immunodiagnostics and vaccine efficacy. A novel genome based strategy for antigen discovery is to relate what is highly expressed by bacilli in vivo or in vitro, to what is ...
Gideon, Hannah Priyadarshini
core  

Molecular basis of the differences in binding properties of the highly related C-type lectins DC-SIGN and L-SIGN to Lewis X trisaccharide and Schistosoma mansoni egg antigens.

, 2004
The dendritic cell-specific C-type lectin DC-SIGN functions as a pathogen receptor that recognizes Schistosoma mansoni egg antigens through its major glycan epitope Galbeta1,4(Fucalpha1,3)GlcNAc (Lex).
Imberty, A, Geijtenbeek, T.B.H., Geijtenbeek, Teunis B. H., van Vliet, Sandra J., Bank, Christine M. C., Imberty, A., van Liempt, Ellis, Bank, CM, van Kooyk, Yvette, Bank, Christine M C, Vliet, SJ van, van Vliet, S.J., van Die, Irma, van Kooyk, Y., Geijtenbeek, Teunis B H, Die, I.M. van, Imberty, Anne, Van Vliet, Sandra J, Liempt, P.A.G., van Liempt, E., Bank, C.M.C., Kooijk, Y. van, van Die, I.   +22 more
core   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source