Results 111 to 120 of about 1,731,278 (307)

Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates

Revista Brasileira de Hematologia e Hemoterapia
ABO, H, secretor and Lewis histo-blood system genes control the expression of part of the carbohydrate repertoire present in areas of the body occupied by microorganisms.
Luiz Carlos de Mattos
doaj   +1 more source

Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity

, 1996
Helicobacter pylori is involved in gastritis, gastric and duodenal ulcers, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. Earlier studies already suggested a role for autoimmune phenomena in H. pylori-linked disease.
Simoons-Smit, Ina, Townsend, Reid R., Appelmelk, Ben J., Verboom, Theo, Crothers, Jim M., Savio, Antonella, Maaskant, Janneke J., Kuipers, Ernst J., Monteiro, Mario A., De Graaff, Johannes, De Vries, Theodora, Negrini, Riccardo, Tyagarajan, Kamala, Quan, Hu, Tadema, Thea M., Ghiara, Paolo, Moran, Anthony P., Forte, John G., Bloemena, Elisabeth, Aspinall, Gerald O.   +19 more
core   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Losses of expression of the antigens A, Le^a and Le^x and over-expression of Le^y in carcinomas and HG-SIL of the uterine cervix

Diagnostic Pathology, 2008
Background The glycosylation of a great number of molecules, glyco-protein or glycolipids, has been of interest for decades. Objective To compare the expressive patterns of the isoantigenic determinants of histo-blood groups ABH and Lewis in squamous and
Álvarez-Fernández Emilio, Moro-Rodríguez Ernesto   +1 more
doaj   +1 more source

Combining radiotherapy with CAR‐T cell therapy for solid tumors: Challenges, mechanisms, and future directions

Precision Radiation Oncology, EarlyView.
Radiotherapy enhances CAR‐Tcell therapy by increasing antigenicity, improving trafficking, and reshaping the tumor microenvironment. Despite its dual effects, including potential immune suppression, understanding these mechanisms enables the development of strategies to maximize synergy in solid tumors.
Leran Qiu, Xingyu Zhou, Jiao Xue, Xiaokang Zhang, Songbing Qin   +4 more
wiley   +1 more source

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, EarlyView.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Expression of Lewis carbohydrate antigens and chromogranin A in human prostatic cancer

, 2000
The prostate specific antigen (PSA) content, the neuroendocrine differentiation and the Lewis(y) and the expression of related carbohydrate antigens in pathological prostatic tissues were determined.
A. Mariano, V. Macchia, DI CARLO, ANGELINA, A. Oliva, M. D'Armiento, C. Santonastaso   +5 more
core  

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Glycoengineering of host mimicking type-2 LacNAc polymersand Lewis X antigens on bacterial cell surfaces

, 2012
Bacterial carbohydrate structures play a central role in mediating a variety of host-pathogen interactions. Glycans can either elicit protective immune response or lead to escape of immune surveillance by mimicking host structures.
Laacisse, Lamia, Widmalm, Göran, Manuela Mally, Markus Aebi, Fontana, Carolina, Fan, Yao-Yun, Lamia Laacisse, Widmalm, Göran,, Mally, Manuela, Göran Widmalm, Carolina Fontana, LeibundGut-Landmann, Salome, Yao-Yun Fan, Aebi, Markus, LeibundGut-Landmann, Salomé; https://orcid.org/, Salomé LeibundGut-Landmann, Fontana, Carolina,   +16 more
core   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source