Results 41 to 50 of about 18,410 (222)

Effect of Lewis blood group antigen expression on bacterial adherence to COS-1 cells [PDF]

Infection and Immunity, 1994
Epithelial cells from secretor individuals demonstrate decreased bacterial adherence compared with cells from nonsecretors. Lewis blood group antigen expression is one component of the secretor/nonsecretor phenotype and several epidemiologic studies have suggested a link between Lewis blood group antigen phenotype and susceptibility to urinary tract ...
R A, Gaffney, A J, Schaeffer, B E, Anderson, J L, Duncan   +3 more
openaire   +2 more sources

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Prevalence of Red Blood Cell Major Blood Group Antigens and Phenotypes among Omani Blood Donors

Oman Medical Journal, 2019
Objectives: Most literature on the frequencies of red blood cell (RBC) phenotypes are published in Europeans and Africans countries, with the frequencies in the Omani population unknown. We sought to determine the prevalence of RBC blood group phenotypes
Arwa Z. Al-Riyami, Ali Al-Marhoobi, Saif Al-Hosni, Sabah Al Mahrooqi, Michael Schmidt, Sheila O’Brien, Murtadha Al-Khabori   +6 more
doaj   +1 more source

The O-Linked Glycome and Blood Group Antigens ABO on Mucin-Type Glycoproteins in Mucinous and Serous Epithelial Ovarian Tumors. [PDF]

PLoS ONE, 2015
Mucins are heavily O-glycosylated proteins where the glycosylation has been shown to play an important role in cancer. Normal epithelial ovarian cells do not express secreted mucins, but their abnormal expression has previously been described in ...
Varvara Vitiazeva, Jayesh J Kattla, Sarah A Flowers, Sara K Lindén, Pushpa Premaratne, Birgitta Weijdegård, Karin Sundfeldt, Niclas G Karlsson   +7 more
doaj   +1 more source

Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife

Biological Reviews, EarlyView.
ABSTRACT Highly pathogenic avian influenza (HPAI) has become a critical threat to wildlife, shifting from a seasonal epizootic to a persistent, year‐round panzootic with global consequences. Here, we summarise the origin, evolutionary mechanisms, and expanding host range of the current H5N1 virus (clade 2.3.4.4b) and assess its impact on wildlife. Over
Ulrich Knief, Sandra Bouwhuis, Anja Globig, Anne Günther, Wouter Courtens   +4 more
wiley   +1 more source

Changes of the expression of Lewis blood group antigens in glycoproteins of renal cancer tissues [PDF]

Acta Biochimica Polonica, 2013
Sialic acid and sialyl Lewisa/x are found on N- and O-glycans of many human malignant cells. Carbohydrate antigens can be used as tumor markers, and an increase of their levels in cancer cells is associated with tumor progression. The aim of this study was to assess the level of some Lewis blood group antigens on glycoproteins in tumor (cancer tissue),
Małgorzata, Borzym-Kluczyk, Iwona, Radziejewska   +1 more
openaire   +4 more sources

Elimination of Fusobacterium nucleatum With Biomimetic Nanoparticles to Reverse Tumor Immunosuppression and Enhance Colorectal Cancer Therapy

Exploration, EarlyView.
Tumor‐related pathogenic bacteria can affect the treatment efficiency of tumors. Therefore, we have designed a nanoparticle that can accurately target tumor cells and related pathogenic bacteria, reverse the immunosuppressive effect of pathogenic bacteria on tumors, and synergistically enhance tumor treatment efficiency through sonodynamic therapy ...
Mengting Zhou, Jiahao Du, Cheng Li, Yefei Zhu, Kairuo Wang, Keyi Wen, Yuanyuan Zhang, Sy‐Tsong Dean Chueng, Qian Chen, Yang Zhang, Huanlong Qin   +10 more
wiley   +1 more source

Norovirus Gastroenteritis Outbreak with a Secretor-independent Susceptibility Pattern, Sweden

Emerging Infectious Diseases, 2010
Norovirus (NoV) is recognized as the commonest cause of acute gastroenteritis among adults. Susceptibility to disease has been associated with histo-blood group antigens and secretor status; nonsecretors are almost completely resistant to disease.
Johan Nordgren, Elin Kindberg, Per-Eric Lindgren, Andreas Matussek, Lennart Svensson   +4 more
doaj   +1 more source

Infant Gut Microbial Metagenome Mining of α-l-Fucosidases with Activity on Fucosylated Human Milk Oligosaccharides and Glycoconjugates

Microbiology Spectrum, 2022
The gastrointestinal microbiota members produce α-l-fucosidases that play key roles in mucosal, human milk, and dietary oligosaccharide assimilation. Here, 36 open reading frames (ORFs) coding for putative α-l-fucosidases belonging to glycosyl hydrolase ...
Eva M. Moya-Gonzálvez, Nazaret Peña-Gil, Antonio Rubio-del-Campo, José M. Coll-Marqués, Roberto Gozalbo-Rovira, Vicente Monedero, Jesús Rodríguez-Díaz, María J. Yebra   +7 more
doaj   +1 more source

Expression of Lewis blood group antigens in cancerous and non-cancerous liver.

Japanese journal of cancer research : Gann, 1987
The expression of Lewis blood group antigens, Lewisa, Lewisb, Lewisx and Lewisy, in 40 non-cancerous livers and in 20 hepatocellular carcinomas (HCC), 5 cholangiocarcinomas (CC), and 6 combined hepatocellular and cholangiocarcinomas (Comb) was studied by immunohistochemistry using monoclonal antibodies.
KANAI, Toshio, HIROHASHI, Setsuo, UPTON, Melissa P., INO, Yoshinori, SHIMOSATO, Yukio   +4 more
openaire   +2 more sources