Results 91 to 100 of about 48,220 (193)
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai +11 more
wiley +1 more source
Advancements in Inorganic Chiral Nanomaterials for Anti‐Tumor Immunotherapy
Schematic illustration of how inorganic chiral nanomaterials enhance immune activation to promote tumor cell elimination through targeted delivery, immunogenic cell death, and immune microenvironment modulation. ABSTRACT While the past decade has witnessed unprecedented technological advancements, cancer remains a major health threat, with conventional
Siyu Chen +9 more
wiley +1 more source
Multifiber Array‐Based Photometry System for Multiregional Functional Mapping in the Mouse Brain
Existing fiber photometry approaches suffer from invasiveness and limited scalability. A newly developed multifiber array‐based photometry system allows targeting multiple brain regions with less invasiveness. The system was validated in two jGCaMP8s‐expressing mouse lines by monitoring GABAergic neural population activity across multiple brain regions
Manil Bradai +4 more
wiley +1 more source
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs +7 more
wiley +1 more source
Selectin ligand sialyl-Lewis x antigen drives metastasis of hormone-dependent breast cancers. [PDF]
Julien S +13 more
europepmc +1 more source
Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin +2 more
wiley +1 more source
Abstract Ischemia‐reperfusion injury (IRI) is a prevalent condition that predominantly afflicts hospitalized patients, inducing acute kidney injury (AKI). In recent years, complement 5 (C5) and its anaphylatoxin receptor C5aR1 have been implicated in driving kidney IRI and loss of function.
Madison McGraw +5 more
wiley +1 more source
Development and characterization of a specific IgG monoclonal antibody toward the Lewis x antigen using splenocytes of Schistosoma mansoni-infected mice. [PDF]
Mandalasi M +5 more
europepmc +1 more source
Lewis A Lewis X is a Tumor Associated Carbohydrate Antigen specifically expressed on the surface of squamous lung carcinoma cells. Because Carbohydrates are involved in immune response, this characteristic makes it a potential target for carbohydrate-based vaccine design.
openaire +1 more source
ObjectiveTo observe the effect of electroacupuncture (EA) of “Zusanli” (ST36) and “Sanyinjiao” (SP6) on cancer pain and concomitant negative emotion in cancer pain model mice, and to explore its molecular mechanisms in the basolateral amygdala (BLA) by ...
LIU Wen-hao +7 more
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