Results 91 to 100 of about 48,220 (193)

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

open access: yesVIEW, Volume 7, Issue 3, June 2026.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai   +11 more
wiley   +1 more source

Advancements in Inorganic Chiral Nanomaterials for Anti‐Tumor Immunotherapy

open access: yesCancer Science, Volume 117, Issue 6, Page 1543-1553, June 2026.
Schematic illustration of how inorganic chiral nanomaterials enhance immune activation to promote tumor cell elimination through targeted delivery, immunogenic cell death, and immune microenvironment modulation. ABSTRACT While the past decade has witnessed unprecedented technological advancements, cancer remains a major health threat, with conventional
Siyu Chen   +9 more
wiley   +1 more source

Multifiber Array‐Based Photometry System for Multiregional Functional Mapping in the Mouse Brain

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 12, June 2026.
Existing fiber photometry approaches suffer from invasiveness and limited scalability. A newly developed multifiber array‐based photometry system allows targeting multiple brain regions with less invasiveness. The system was validated in two jGCaMP8s‐expressing mouse lines by monitoring GABAergic neural population activity across multiple brain regions
Manil Bradai   +4 more
wiley   +1 more source

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

open access: yesThe FEBS Journal, Volume 293, Issue 11, Page 3187-3210, June 2026.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs   +7 more
wiley   +1 more source

Selectin ligand sialyl-Lewis x antigen drives metastasis of hormone-dependent breast cancers. [PDF]

open access: yesCancer Res, 2011
Julien S   +13 more
europepmc   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

open access: yesJournal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1722-1742, June 2026.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin   +2 more
wiley   +1 more source

Novel interactions between the C5‐C5aR1 Axis and IF1: Implications for kidney mitochondrial physiology and ischemia–reperfusion injury

open access: yesPhysiological Reports, Volume 14, Issue 11, June 2026.
Abstract Ischemia‐reperfusion injury (IRI) is a prevalent condition that predominantly afflicts hospitalized patients, inducing acute kidney injury (AKI). In recent years, complement 5 (C5) and its anaphylatoxin receptor C5aR1 have been implicated in driving kidney IRI and loss of function.
Madison McGraw   +5 more
wiley   +1 more source

Synthesis of Tetrasaccharide and Pentasaccharide Fragments of the Tumor-Associated Carbohydrate Antigen Lewis A Lewis X

open access: yes, 2013
Lewis A Lewis X is a Tumor Associated Carbohydrate Antigen specifically expressed on the surface of squamous lung carcinoma cells. Because Carbohydrates are involved in immune response, this characteristic makes it a potential target for carbohydrate-based vaccine design.
openaire   +1 more source

Molecular mechanism of basolateral amygdala involved in electroacupuncture-induced amelioration of cancer pain and concomitant depression based on transcriptomics techniques

open access: yes针刺研究
ObjectiveTo observe the effect of electroacupuncture (EA) of “Zusanli” (ST36) and “Sanyinjiao” (SP6) on cancer pain and concomitant negative emotion in cancer pain model mice, and to explore its molecular mechanisms in the basolateral amygdala (BLA) by ...
LIU Wen-hao   +7 more
doaj  

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