Results 81 to 90 of about 48,220 (193)

Apple Pomace Pectin for Gastroprotective Nutraceutical Delivery: Structure–Function Relationships and Nano/Microencapsulation Strategies for Gastric Ulcer Management

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
Apple pomace pectin is explored as a sustainable and multifunctional biomaterial for gastric ulcer management. Its unique structural features confer mucoadhesive, anti‐inflammatory, antioxidant, and anti‐Helicobacter pylori activities while enabling nano/microencapsulation of therapeutic agents.
Akash Dhiman   +6 more
wiley   +1 more source

Zinc Oxide Nanoparticles for Food Applications: From Synthesis and Functional Properties to Safety and Sustainability

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
Green and conventional synthesis routes produce ZnO nanoparticles with tunable physicochemical properties for food applications, ZnO‐NPs enhance antimicrobial activity, UV protection, and food preservation through ROS generation and ZN2+ release. However, particle dissolution, migration, cytotoxicity, and environmental concerns highlight the need for ...
Liza Akter   +6 more
wiley   +1 more source

Nanozymes at the Bio‐Nano Interface: From Synthesis, Defect Engineering, Catalytic Behavior in Biological Microenvironments, and Biosafety Implications

open access: yesAdvanced Materials Interfaces, Volume 13, Issue 11, 9 June 2026.
Nanozymes (NZs) have emerged as versatile artificial enzymes with tunable catalytic properties driven by atomic coordination, defect engineering, and surface chemistry. This review presents a bio–nano interface framework linking synthesis strategies, structural design, and catalytic behavior within complex biological microenvironments.
Karen Guadalupe Quintero‐Garrido   +6 more
wiley   +1 more source

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin   +10 more
wiley   +1 more source

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

open access: yesAdvanced Science, Volume 13, Issue 31, 4 June 2026.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao   +12 more
wiley   +1 more source

Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy

open access: yesAggregate, Volume 7, Issue 6, June 2026.
Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao   +5 more
wiley   +1 more source

The Supporting Role of Natural Products as Effective Adjuvants in Cancer Immunotherapy

open access: yeseFood, Volume 7, Issue 3, June 2026.
Natural products, as multi‐target and low‐toxicity adjuvants, enhance immune checkpoint inhibitor responses and reduce immune‐related adverse events through T cell reprogramming, microenvironment remodeling, and microbiota‐immune modulation. ABSTRACT Immune checkpoint inhibitors (ICIs) have revolutionized the treatment landscape of malignant tumors ...
Boyang Liu   +6 more
wiley   +1 more source

Expression of Lewis^x, Sialylated Lewis^x, Lewis^a, and Sialylated Lewis^a Antigens in Human Lung Carcinoma

open access: yesExpression of Lewis^x, Sialylated Lewis^x, Lewis^a, and Sialylated Lewis^a Antigens in Human Lung Carcinoma
長崎大学学位論文 [学位記番号]博(医)乙第1071号 [学位授与年月日]平成3年8月31日 (1991-08-31)
openaire  

Vacuolization as a Novel Approach to Cancer Therapy

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak   +9 more
wiley   +1 more source

Stearoyl‐CoA Desaturase‐1 Drives Tumor Growth by Interacting With Histone Deacetylase‐2 and Deacetylating Nucleophosmin‐1

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Hypoxia induces SCD1 and PLIN2 to drive lipid droplet‐dependent metabolic adaptation in cancer cells. PLIN2 supports survival under stress, whereas SCD1 promotes proliferation upon reoxygenation and remodels the acetylome via HDAC2‐mediated NPM1 deacetylation and destabilization.
Coline Wery   +15 more
wiley   +1 more source

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