Results 141 to 150 of about 80,492 (287)

Elevation of Stearoyl‐Coenzyme A Desaturase and Monounsaturated Fatty Acids in Parkinson's Disease Serum

Movement Disorders, EarlyView.
Abstract Background Emerging evidence indicates that dysregulation of monounsaturated fatty acids (MUFAs), synthesized by the enzyme stearoyl‐coenzyme A desaturase (SCD), impacts on α‐synuclein pathology in the Parkinson's disease (PD) brain. Objective The objective of this study was to analyze SCD and MUFA‐enriched lipids in the periphery of patients ...
Finula I. Isik, Russell Pickford, Michelle Chua, Simon J.G. Lewis, Nicolas Dzamko, Woojin Scott Kim   +5 more
wiley   +1 more source

Differential Progression of Neuroinflammation in Patients with Isolated Rapid‐Eye‐Movement Sleep Behavior Disorder

Movement Disorders, EarlyView.
Abstract Background Neuroinflammation, measured using [11C](R)‐PK11195 positron emission tomography (PET), has been reported in isolated rapid‐eye‐movement sleep behavior disorder (iRBD), but its temporal progression is unknown. Objective The aim was to assess longitudinal progression of neuroinflammation in iRBD patients and its relationship with ...
Andreas Myhre Baun, Alex Iranzo, Miriam Højholt Terkelsen, Rainer Hinz, Morten Gersel Stokholm, Kristian Stær, Mónica Serradel, Marit Otto, Kristina Bacher Svendsen, Alicia Garrido, Dolores Vilas, Arne Møller, Carles Gaig, Eduardo Tolosa, David J. Brooks, Per Borghammer, Simon Fristed Eskildsen, Nicola Pavese   +17 more
wiley   +1 more source

Lewy Body Dementia [PDF]

Journal of the Royal Society of Medicine, 1997
openaire   +2 more sources

Macroscale Gradient‐Informed Neural Oscillation Topography in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is characterized by large‐scale disruptions in beta and gamma oscillations. Although subcortical beta power is an established biomarker for current adaptive deep brain stimulation (aDBS), it may not fully capture the global pathophysiological burden and the macroscale hierarchical reorganization of the ...
Hao Ding, Ke Xie, Manuel Bange, Hannah Kühne, Jenny Blech, Bahman Nasseroleslami, Jens Volkmann, Sergiu Groppa, Muthuraman Muthuraman   +8 more
wiley   +1 more source

A novel stable transgenic zebrafish line expressing mCherry-tagged human alpha-synuclein in the nervous system and exhibiting all the key features of Lewy body disorders at larval stage

Neurobiology of Disease
Lewy Bodies, proteinaceous inclusions containing α-Synuclein fibrillary aggregates, are defining neuropathological hallmarks of Parkinson's disease and Dementia with Lewy Bodies.
Silvia Zini, Alessia Muscò, Francesca Longhena, Gaia Faustini, Chiara Tobia, Giuseppe Borsani, Maria Grazia Spillantini, Daniela Zizioli, Arianna Bellucci   +8 more
doaj   +1 more source

Demencia con cuerpos de Lewy: Presentación de 1 caso Dementia with lewy bodies: A case report

Revista Cubana de Medicina, 2004
Se ha planteado que la demencia constituye la cuarta causa básica de muerte en países del primer mundo. La demencia con cuerpos de Lewy (DCL) constituye la segunda causa de demencia en estudios necrópsicos actuales, superada solo por la enfermedad de ...
David Cubero Rego, Osiris Cubero Menéndez, Mylene Cabrera Mehn, Reinaldo Álvarez Santana   +3 more
doaj  

Kinetic Compensation of Barrel Launch Under High‐Speed Solid‐Phase Particulate Impacts

International Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT An accurate launch‐dynamics computational method is critical for barrel weapon service life assessment and multiphase physics field refinement. Given the lack of studies on the solid‐phase buildup behavior at the projectile base, this paper provides an improved method for calculating the launching dynamics under high pressure and high speed ...
Zhiyi He, Guolai Yang, Quanzhao Sun, Shuli Li   +3 more
wiley   +1 more source

Numerical Insights Into the Resistance Reduction Mechanisms of Forward Tapered Transoms in High‐Speed Catamaran: A Computational Fluid Dynamics‐Based Study

International Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT This study investigates the hydrodynamic influence of forward transom tapering on a displacement catamaran hull using computational fluid dynamics (CFD) simulations. Five taper configurations ranging from a vertical transom base design to a fully tapered stern (1.00B) were evaluated over a wide Froude number range (Fr = .3 to 1.0).
Chalermkiat Nuchturee, Chairat Napasaksri, Ramil Kesvarakul, Sarawuth Srinakaew   +3 more
wiley   +1 more source

Matters Arising ‘Lewy body disease or diseases with Lewy bodies?’

npj Parkinson's Disease, 2022
Kurt A. Jellinger
doaj   +1 more source

Pleiotropic effects of variants in dementia genes in Parkinson disease [PDF]

, 2018
Benitez, Bruno A, Budde, John, Cooper, Breanna, Cruchaga, Carlos, David, Albert A, Diez-Fairen, Monica, Dube, Umber, Fernandez, Maria V, Ibanez, Laura, Ortega-Cubero, Sara, Pastor, Pau, Perlmutter, Joel S   +11 more
core   +2 more sources