Results 171 to 180 of about 8,460,931 (324)

Parkinson\u27s disease, lewy body

open access: yes, 1997
Parkinson\u27s disease, lewy body. A 38-82.

core  

Levodopa and Melanoma: Practical Recommendations for Parkinson's Disease—International Parkinson and Movement Disorder Society Scientific Issues Committee Viewpoint

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Giorgia Sciacca   +27 more
wiley   +1 more source

Calibration‐Free Estimation of Cerebrovascular Reactivity From Resting‐State BOLD fMRI Using Reconstructed Respiratory Fluctuations

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Cerebrovascular reactivity (CVR) provides an important index of vascular health and is conventionally quantified using a hypercapnic gas or breath‐hold challenge in conjunction with blood‐oxygen‐level‐dependent functional magnetic resonance imaging (BOLD‐fMRI).
Abdoljalil Addeh   +9 more
wiley   +1 more source

Therapeutic Impact of GLP‐1 Receptor Agonists on Parkinson's Disease: A Scoping Review

open access: yesNeurology and Clinical Neuroscience, EarlyView.
ABSTRACT No disease‐modifying treatment exists for Parkinson's disease (PD). Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have gained attention as promising candidates for neuroprotection, given documented expression of GLP‐1 receptors within the central nervous system and the contribution of brain insulin resistance to dopaminergic ...
João Pedro Henriques   +4 more
wiley   +1 more source

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Tewdwr: Eponymous Ancestor of the Tudor Dynasty

open access: yesHistory, EarlyView.
Abstract The standard derivation of the dynastic name Tudor from Welsh Tudur, surname of the grandfather of Henry VII, is problematic on phonological grounds, as well as the fact that Tudur was never used as a surname by Henry himself, being attributed to him only by his enemies with implication of lowly origins.
DAFYDD JOHNSTON
wiley   +1 more source

Expression of α ⁃synuclein in the spinal cord of Alzheimer's disease

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2010
Objective To investigate the characteristics of α⁃synucleinopathy in the spinal cord of patients with Alzheimer's disease (AD). Methods HE staining and immunohistochemistry staining were used to determine the expression of α⁃synuclein in the spinal cord (
Yan⁃jun GUO   +7 more
doaj  

Human brain matters: Navigating the neuropathology of COVID‐19

open access: yesBrain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland   +4 more
wiley   +1 more source

Data‐driven thresholds for standardized classification of severe Alzheimer's disease neuropathology using digital neuropathology

open access: yesBrain Pathology, EarlyView.
We generated digital pathologic algorithms (AI‐based modules that can be freely shared) to: optimize the sampling (ROI) for diagnosis of ADNC‐related tau pathology; compare/transition between Aperio and HALO platforms; and rationalize severe Braak NFT staging, so that all Braak‐VI cases had dementia, and all Braak‐V cases had MCI or dementia.
Ryan K. Shahidehpour   +10 more
wiley   +1 more source

Wasteosomes accumulate in periventricular white matter hyperintensities and exhibit complex relationships with mixed pathology, sclerotic index, and perivascular space

open access: yesBrain Pathology, EarlyView.
In a mixed diagnostic cohort of pathologically diagnosed Alzheimer's disease, cerebrovascular disease, mixed pathology, and control tissue, we connected the histopathological wasteosome profile in periventricular (PV) brain sections to 7T FLAIR‐MRI confirmed PV white matter hyperintensities (WMHs), vascular stenosis and perivascular space size ...
Nikita Ollen‐Bittle   +7 more
wiley   +1 more source

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